Detalhe da pesquisa
1.
A newly synthesized nickel chelate can selectively target and overcome multidrug resistance in cancer through redox imbalance both in vivo and in vitro.
J Biol Inorg Chem
; 22(8): 1223-1249, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29063196
2.
Modulation of cell death in human colorectal and breast cancer cells through a manganese chelate by involving GSH with intracellular p53 status.
Mol Cell Biochem
; 427(1-2): 35-58, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28012015
3.
A Novel Approach of Synthesizing and Evaluating the Anticancer Potential of Silver Oxide Nanoparticles in vitro.
Chemotherapy
; 62(5): 279-289, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28490010
4.
In vitro and in vivo Anticancer Effects of a Novel 9-Phenyldibenzo[a,c]phenazin-9-ium Cation and Its Ligands.
Chemotherapy
; 60(4): 261-6, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25926067
5.
A copper chelate selectively triggers apoptosis in myeloid-derived suppressor cells in a drug-resistant tumor model and enhances antitumor immune response.
Immunopharmacol Immunotoxicol
; 36(2): 165-75, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24611750
6.
Selective induction of apoptosis in various cancer cells irrespective of drug sensitivity through a copper chelate, copper N-(2 hydroxy acetophenone) glycinate: crucial involvement of glutathione.
Biometals
; 26(3): 517-34, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23733180
7.
Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines.
Anticancer Res
; 43(3): 1031-1041, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854510
8.
The molecular interaction of a copper chelate with human P-glycoprotein.
Mol Cell Biochem
; 364(1-2): 309-20, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22258826
9.
Iron N-(2-hydroxy acetophenone) glycinate (FeNG), a non-toxic glutathione depletor circumvents doxorubicin resistance in Ehrlich ascites carcinoma cells in vivo.
Biometals
; 25(1): 149-63, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21915630
10.
A novel tin based hydroxamic acid complex induces apoptosis through redox imbalance and targets Stat3/JNK1/MMP axis to overcome drug resistance in cancer.
Free Radic Res
; 55(9-10): 1018-1035, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34865583
11.
The role of copper in drug-resistant murine and human tumors.
Biometals
; 22(2): 377-84, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18956143
12.
Induction of apoptosis in human colorectal cancer cell line, HCT-116 by a vanadium- Schiff base complex.
Biomed Pharmacother
; 92: 509-518, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575808
13.
A zinc Schiff base complex inhibits cancer progression both in vivo and in vitro by inducing apoptosis.
Environ Toxicol Pharmacol
; 56: 383-392, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29145169
14.
Induction of intrinsic and extrinsic apoptosis through oxidative stress in drug-resistant cancer by a newly synthesized Schiff base copper chelate.
Free Radic Res
; 50(4): 426-46, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26733073
15.
A copper chelate induces apoptosis and overcomes multidrug resistance in T-cell acute lymphoblastic leukemia through redox imbalance and inhibition of EGFR/PI3K/Akt expression.
Biomed Pharmacother
; 84: 71-92, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27639544
16.
Co-administration of glycyrrhizic acid with the antileishmanial drug sodium antimony gluconate (SAG) cures SAG-resistant visceral leishmaniasis.
Int J Antimicrob Agents
; 45(3): 268-77, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25600891
17.
The role of a Schiff base scaffold, N-(2-hydroxy acetophenone) glycinate-in overcoming multidrug resistance in cancer.
Eur J Pharm Sci
; 51: 96-109, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24044945
18.
Mn complex-mediated enhancement of antitumor response through modulating myeloid-derived suppressor cells in drug-resistant tumor.
In Vivo
; 28(5): 909-18, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189907
19.
ROS and RNS induced apoptosis through p53 and iNOS mediated pathway by a dibasic hydroxamic acid molecule in leukemia cells.
Eur J Pharm Sci
; 52: 146-64, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24269727
20.
Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells.
Immunobiology
; 218(5): 718-24, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22995935