Detalhe da pesquisa
1.
Association of Plasma Phosphorylated Tau With the Response to Neflamapimod Treatment in Patients With Dementia With Lewy Bodies.
Neurology
; 101(17): e1708-e1717, 2023 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657939
2.
Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.
Nat Commun
; 13(1): 5308, 2022 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36130946
3.
A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer's disease.
Alzheimers Res Ther
; 13(1): 106, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34044875
4.
Pharmacometrics of clobazam in pediatrics: Prediction of effective clobazam doses for Dravet syndrome.
Epilepsy Res
; 157: 106182, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31563030
5.
An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease.
Ann Clin Transl Neurol
; 5(4): 464-473, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29687023
6.
Live-cell phenotypic-biomarker microfluidic assay for the risk stratification of cancer patients via machine learning.
Nat Biomed Eng
; 2(10): 761-772, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30854249
7.
An integrative population pharmacokinetics approach to the characterization of the effect of hepatic impairment on clobazam pharmacokinetics.
J Clin Pharmacol
; 56(2): 213-22, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26139309
8.
Drug-metabolism mechanism: Knowledge-based population pharmacokinetic approach for characterizing clobazam drug-drug interactions.
J Clin Pharmacol
; 56(3): 365-74, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26224203
9.
Phenotypic characterization of resistant Val36 variants of hepatitis C virus NS3-4A serine protease.
Antimicrob Agents Chemother
; 52(1): 110-20, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17938182
10.
Antiviral activity of telaprevir (VX-950) and peginterferon alfa-2a in patients with hepatitis C.
Hepatology
; 46(3): 640-8, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17879366
11.
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir.
Gastroenterology
; 132(5): 1767-77, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17484874
12.
A random sampling approach for robust estimation of tissue-to-plasma ratio from extremely sparse data.
AAPS J
; 7(1): E249-58, 2005 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16146346
13.
Data supplementation: a pharmacokinetic/pharmacodynamic knowledge creation approach for characterizing an unexplored region of the response surface.
Pharm Res
; 22(4): 523-31, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15846459