Detalhe da pesquisa
1.
Discovery of N-benzylbenzamide-based allosteric inhibitors of Aurora kinase A.
Bioorg Med Chem
; 102: 117658, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460487
2.
In vitro modeling of liver fibrosis with 3D co-culture system using a novel human hepatic stellate cell line.
Biotechnol Bioeng
; 120(5): 1241-1253, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639871
3.
Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase.
J Enzyme Inhib Med Chem
; 38(1): 2217695, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37246947
4.
In vitro and in vivo neuroprotective effect of novel mPGES-1 inhibitor in animal model of Parkinson's disease.
Bioorg Med Chem Lett
; 74: 128920, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931244
5.
Identification of highly selective type II kinase inhibitors with chiral peptidomimetic tails.
J Enzyme Inhib Med Chem
; 37(1): 1257-1277, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484863
6.
Dieckol Isolated from Eisenia bicyclis Ameliorates Wrinkling and Improves Skin Hydration via MAPK/AP-1 and TGF-ß/Smad Signaling Pathways in UVB-Irradiated Hairless Mice.
Mar Drugs
; 20(12)2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36547926
7.
Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1.
Proc Natl Acad Sci U S A
; 116(19): 9423-9432, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000600
8.
Genetic interactions reveal the antagonistic roles of FT/TSF and TFL1 in the determination of inflorescence meristem identity in Arabidopsis.
Plant J
; 99(3): 452-464, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30943325
9.
Optimization of 3D hydrogel microenvironment for enhanced hepatic functionality of primary human hepatocytes.
Biotechnol Bioeng
; 117(6): 1864-1876, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32162676
10.
Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers.
Bioorg Med Chem
; 28(11): 115491, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327350
11.
Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches.
Bioorg Chem
; 103: 104121, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32745753
12.
Cationic amino acid transporter PQLC2 is a potential therapeutic target in gastric cancer.
Cancer Sci
; 110(4): 1453-1463, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30729615
13.
Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids.
J Hepatol
; 71(5): 970-985, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31299272
14.
Developing scalable cultivation systems of hepatic spheroids for drug metabolism via genomic and functional analyses.
Biotechnol Bioeng
; 116(6): 1496-1508, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737956
15.
Anti-Colitic Effects of Ethanol Extract of Persea americana Mill. through Suppression of Pro-Inflammatory Mediators via NF-κB/STAT3 Inactivation in Dextran Sulfate Sodium-Induced Colitis Mice.
Int J Mol Sci
; 20(1)2019 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30621304
16.
ß-Caryophyllene in the Essential Oil from Chrysanthemum Boreale Induces G1 Phase Cell Cycle Arrest in Human Lung Cancer Cells.
Molecules
; 24(20)2019 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31635244
17.
A liver-specific gene expression panel predicts the differentiation status of in vitro hepatocyte models.
Hepatology
; 66(5): 1662-1674, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640507
18.
Panaxydol Derived from Panax ginseng Inhibits G1 Cell Cycle Progression in Non-small Cell Lung Cancer via Upregulation of Intracellular Ca2+ Levels.
Biol Pharm Bull
; 41(11): 1701-1707, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30381670
19.
Novel Rhodanine Derivative, 5-[4-(4-Fluorophenoxy) phenyl]methylene-3-{4-[3-(4-methylpiperazin-1-yl) propoxy]phenyl}-2-thioxo-4-thiazolidinone dihydrochloride, Induces Apoptosis via Mitochondria Dysfunction and Endoplasmic Reticulum Stress in Human Colon Cancer Cells.
Molecules
; 23(11)2018 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30404185
20.
23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells.
Molecules
; 23(12)2018 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30551620