Detalhe da pesquisa
1.
Metabolomics hallmarks OPA1 variants correlating with their in vitro phenotype and predicting clinical severity.
Hum Mol Genet
; 29(8): 1319-1329, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202296
2.
Metabolomic Sexual Dimorphism of the Mouse Brain is Predominantly Abolished by Gonadectomy with a Higher Impact on Females.
J Proteome Res
; 20(5): 2772-2779, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851846
3.
Increased Protein S-Glutathionylation in Leber's Hereditary Optic Neuropathy (LHON).
Int J Mol Sci
; 21(8)2020 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32344771
4.
Lipidomics Reveals Triacylglycerol Accumulation Due to Impaired Fatty Acid Flux in Opa1-Disrupted Fibroblasts.
J Proteome Res
; 18(7): 2779-2790, 2019 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199663
5.
CLUH couples mitochondrial distribution to the energetic and metabolic status.
J Cell Sci
; 130(11): 1940-1951, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28424233
6.
Metabolomics and Lipidomics Profiling of a Combined Mitochondrial Plus Endoplasmic Reticulum Fraction of Human Fibroblasts: A Robust Tool for Clinical Studies.
J Proteome Res
; 17(1): 745-750, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29111762
7.
The metabolomic signature of Leber's hereditary optic neuropathy reveals endoplasmic reticulum stress.
Brain
; 139(11): 2864-2876, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27633772
8.
Resveratrol induces a mitochondrial complex I-dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
J Biol Chem
; 288(51): 36662-75, 2013 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24178296
9.
Dominant ACO2 mutations are a frequent cause of isolated optic atrophy.
Brain Commun
; 3(2): fcab063, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34056600
10.
Metabolomic signature of the seminal plasma in men with severe oligoasthenospermia.
Andrology
; 8(6): 1859-1866, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32770844
11.
Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways.
Cells
; 9(6)2020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32466566
12.
Metabolomics reveals highly regional specificity of cerebral sexual dimorphism in mice.
Prog Neurobiol
; 184: 101698, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557505
13.
Sickle Cell Disease: Metabolomic Profiles of Vaso-Occlusive Crisis in Plasma and Erythrocytes.
J Clin Med
; 9(4)2020 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32290473
14.
A Plasma Metabolomic Profiling of Exudative Age-Related Macular Degeneration Showing Carnosine and Mitochondrial Deficiencies.
J Clin Med
; 9(3)2020 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32120889
15.
Metabo-lipidomics of Fibroblasts and Mitochondrial-Endoplasmic Reticulum Extracts from ALS Patients Shows Alterations in Purine, Pyrimidine, Energetic, and Phospholipid Metabolisms.
Mol Neurobiol
; 56(8): 5780-5791, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30680691
16.
Warburg-like effect is a hallmark of complex I assembly defects.
Biochim Biophys Acta Mol Basis Dis
; 1865(9): 2475-2489, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31121247
17.
The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency.
Sci Rep
; 8(1): 11528, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30068998
18.
Targeted Metabolomics Reveals Early Dominant Optic Atrophy Signature in Optic Nerves of Opa1delTTAG/+ Mice.
Invest Ophthalmol Vis Sci
; 58(2): 812-820, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28159969
19.
Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice.
PLoS One
; 10(12): e0144290, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684010
20.
Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency.
Int J Biochem Cell Biol
; 65: 91-103, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26024641