RESUMO
OBJECTIVE: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. METHOD: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer's disease (AD) patients and 30 were considered as cognitively normal individuals. RESULTS: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. CONCLUSION: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.
Assuntos
Transtornos Cognitivos/diagnóstico , Inquéritos e Questionários , Atividades Cotidianas , Idoso , Doença de Alzheimer/diagnóstico , Doença de Alzheimer/fisiopatologia , Brasil , Estudos de Casos e Controles , Transtornos Cognitivos/fisiopatologia , Comparação Transcultural , Feminino , Avaliação Geriátrica/métodos , Humanos , Masculino , Curva ROC , Sensibilidade e Especificidade , Índice de Gravidade de Doença , TraduçõesRESUMO
Summary Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument. Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer's disease (AD) patients and 30 were considered as cognitively normal individuals. Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2. Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.
Resumo Objetivo: Tradução, adaptação transcultural para o português brasileiro e aplicação da escala Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) como instrumento de triagem cognitiva. Método: Retrotradução associada ao método bilíngue e de pré-teste. A amostra foi constituída por 95 idosos e seus respectivos acompanhantes, sendo 30 controles, 32 portadores de comprometimento cognitivo leve (CCL) e 33 portadores de demência de Alzheimer (DA) em fase inicial. Resultados: Um pequeno número de modificações ocorreu na escala. O coeficiente alpha de Cronbach foi 0,89. O grupo controle pontuou 72,9, seguido pelo CCL (65,1) e pelo DA (55,9), valor p<0,001. A curva ROC demonstrou valor de 0,89. Com o ponto de corte de 72, observamos sensibilidade de 86,2%, especificidade de 70%, valor preditivo positivo de 86,2%, valor preditivo negativo de 70%, razão de verossimilhança positiva de 2,9 e razão de verossimilhança negativa de 0,2. Conclusão: A escala ADCS-ADL apresenta propriedades psicométricas satisfatórias para discriminar entre DA, CCL e cognição normal.