What limitations are reported in short articles in social and personality psychology?

Every research project has limitations. The limitations that authors acknowledge in their articles offer a glimpse into some of the concerns that occupy a field's attention. We examine the types of limitations authors discuss in their published articles by categorizing them according to the four validities framework and investigate whether the field's attention to each of the four validities has shifted from 2010 to 2020. We selected one journal in social and personality psychology (Social Psychological and Personality Science; SPPS), the subfield most in the crosshairs of psychology's replication crisis. We sampled 440 articles (with half of those articles containing a subsection explicitly addressing limitations), and we identified and categorized 831 limitations across the 440 articles. Articles with limitations sections reported more limitations than those without (avg. 2.6 vs. 1.2 limitations per article). Threats to external validity were the most common type of reported limitation (est. 52% of articles), and threats to statistical conclusion validity were the least common (est. 17% of articles). Authors reported slightly more limitations over time. Despite the extensive attention paid to statistical conclusion validity in the scientific discourse throughout psychology's credibility revolution, our results suggest that concerns about statistics-related issues were not reflected in social and personality psychologists' reported limitations. The high prevalence of limitations concerning external validity might suggest it is time that we improve our practices in this area, rather than apologizing for these limitations after the fact. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Ramifications of the COVID-19 Pandemic on Nursing Students' Transition to Practice.

As the COVID-19 pandemic altered the course of nursing education worldwide, it disrupted efforts to transition nursing students to professional practice. The investigators examined clinical nursing faculty members' assessment of senior students' practice strengths and challenges compared to graduates of prior years. Findings demonstrated COVID-19's wide-ranging impacts on nursing students' transition to practice and offered suggestions about the implications for nursing professional development practitioners.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration.

Crystallography driven optimisation of a lead derived from similarity searching of the GSK compound collection resulted in the discovery of quinoline-3-carboxamides as highly potent and selective inhibitors of phosphodiesterase 4B. This series has been optimized to GSK256066, a potent PDE4B inhibitor which also inhibits LPS induced production of TNF-alpha from isolated human peripheral blood mononuclear cells with a pIC(50) of 11.1. GSK256066 also has a suitable profile for inhaled dosing.

Integrating patient safety into health professionals' curricula: a qualitative study of medical, nursing and pharmacy faculty perspectives.

BACKGROUND: As efforts to integrate patient safety into health professional curricula increase, there is growing recognition that the rate of curricular change is very slow, and there is a shortage of research that addresses critical perspectives of faculty who are on the 'front-lines' of curricular innovation. This study reports on medical, nursing and pharmacy teaching faculty perspectives about factors that influence curricular integration and the preparation of safe practitioners. METHODS: Qualitative methods were used to collect data from 20 faculty members (n=6 medical from three universities; n=6 pharmacy from two universities; n=8 nursing from four universities) engaged in medical, nursing and pharmacy education. Thematic analysis generated a comprehensive account of faculty perspectives. RESULTS: Faculty perspectives on key challenges to safe practice vary across the three disciplines, and these different perspectives lead to different priorities for curricular innovation. Additionally, accreditation and regulatory requirements are driving curricular change in medicine and pharmacy. Key challenges exist for health professional students in clinical teaching environments where the culture of patient safety may thwart the preparation of safe practitioners. CONCLUSIONS: Patient safety curricular innovation depends on the interests of individual faculty members and the leveraging of accreditation and regulatory requirements. Building on existing curricular frameworks, opportunities now need to be created for faculty members to act as champions of curricular change, and patient safety educational opportunities need to be harmonises across all health professional training programmes. Faculty champions and practice setting leaders can collaborate to improve the culture of patient safety in clinical teaching and learning settings.