Detalhe da pesquisa
1.
Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis.
N Engl J Med
; 385(25): 2325-2335, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739194
2.
Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis.
N Engl J Med
; 385(25): 2313-2324, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739196
3.
The ASCEND-NHQ randomized trial found positive effects of daprodustat on hemoglobin and quality of life in patients with non-dialysis chronic kidney disease.
Kidney Int
; 103(6): 1180-1192, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868377
4.
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D).
Am J Nephrol
; 54(1-2): 1-13, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739866
5.
Analysis of on-treatment cancer safety events with daprodustat versus conventional erythropoiesis-stimulating agents-post hoc analyses of the ASCEND-ND and ASCEND-D trials.
Nephrol Dial Transplant
; 38(8): 1890-1897, 2023 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565721
6.
Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial.
Nephrol Dial Transplant
; 37(5): 960-972, 2022 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33744933
7.
The ASCEND-ND trial: study design and participant characteristics.
Nephrol Dial Transplant
; 37(11): 2157-2170, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34865143
8.
Daprodustat Compared with Epoetin Beta Pegol for Anemia in Japanese Patients Not on Dialysis: A 52-Week Randomized Open-Label Phase 3 Trial.
Am J Nephrol
; 52(1): 26-35, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33561857
9.
A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis.
BMC Nephrol
; 20(1): 372, 2019 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619187
10.
Anemia and mortality in patients with nondialysis-dependent chronic kidney disease.
BMC Nephrol
; 19(1): 135, 2018 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29890958
11.
Four-Week Studies of Oral Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia.
J Am Soc Nephrol
; 27(4): 1234-44, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494831
12.
Evaluation of Quantitative Computed Tomography Cortical Hip Quadrant in a Clinical Trial With Rosiglitazone: A Potential New Study Endpoint.
J Clin Densitom
; 19(4): 485-491, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27052635
13.
Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients.
BMC Nephrol
; 16: 144, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283069
14.
Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function.
Clin Pharmacol Drug Dev
; 11(5): 562-575, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355447
15.
Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis Patients: ASCEND-TD: A Phase 3 Randomized, Double-Blind, Noninferiority Trial.
Clin J Am Soc Nephrol
; 17(9): 1325-1336, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35918106
16.
Challenges of Conducting Clinical Trials during the SARS-CoV-2 Pandemic: The ASCEND Global Program Experience.
Kidney360
; 3(4): 728-733, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35721625
17.
Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients: A Randomized Clinical Trial.
JAMA Intern Med
; 182(6): 592-602, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377393
18.
Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability Determination.
Clin Pharmacol Drug Dev
; 10(12): 1419-1431, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34713596
19.
Efficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia: A Randomized, Double-Blind, Phase 3 Trial.
Clin J Am Soc Nephrol
; 15(8): 1155-1165, 2020 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723804
20.
Effect of renal function and dialysis modality on daprodustat and predominant metabolite exposure.
Clin Kidney J
; 12(5): 693-701, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31583094