Detalhe da pesquisa
1.
Second generation of pyrimidin-quinolone hybrids obtained from virtual screening acting as sphingosine kinase 1 inhibitors and potential anticancer agents.
Bioorg Chem
; 144: 107112, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237390
2.
Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety.
Int J Mol Sci
; 23(20)2022 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36293443
3.
Design, synthesis, and molecular docking study of novel quinoline-based bis-chalcones as potential antitumor agents.
Arch Pharm (Weinheim)
; 354(9): e2100094, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050547
4.
Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors.
Bioorg Chem
; 94: 103414, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757412
5.
New thiazolyl-pyrazoline derivatives bearing nitrogen mustard as potential antimicrobial and antiprotozoal agents.
Arch Pharm (Weinheim)
; 353(5): e1900351, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32187709
6.
Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity.
Arch Pharm (Weinheim)
; 352(3): e1800298, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30648282
7.
Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents.
Molecules
; 23(3)2018 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29495412
8.
6-(Aryldiazenyl)pyrazolo[1,5-a]pyrimidines as Strategic Intermediates for the Synthesis of Pyrazolo[5,1-b]purines.
J Org Chem
; 81(24): 12364-12373, 2016 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27978735
9.
A new series of antibacterial nitrosopyrimidines: synthesis and structure-activity relationship.
Arch Pharm (Weinheim)
; 348(1): 68-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25413501
10.
Synthesis and in vitro antitumor activity of a novel series of 2-pyrazoline derivatives bearing the 4-aryloxy-7-chloroquinoline fragment.
Molecules
; 19(11): 18656-75, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25405285
11.
Highly efficient and diastereoselective synthesis of new pyrazolylpyrrolizine and pyrazolylpyrrolidine derivates by a three-component domino process.
Molecules
; 19(4): 4284-300, 2014 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24714191
12.
Rosmarinic Acid Present in Lepechinia floribunda and Lepechinia meyenii as a Potent Inhibitor of the Adenylyl Cyclase gNC1 from Giardia lamblia.
Plants (Basel)
; 13(5)2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38475493
13.
Cascade Synthesis of New Indole-Containing Pentacyclic Scaffolds Mediated by Aryl and Iminyl Radicals.
Chem Asian J
; 19(5): e202301111, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38217883
14.
Molecular modeling study of dihydrofolate reductase inhibitors. Molecular dynamics simulations, quantum mechanical calculations, and experimental corroboration.
J Chem Inf Model
; 53(8): 2018-32, 2013 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23834278
15.
Synthesis, antifungal and antitumor activity of novel (Z)-5-hetarylmethylidene-1,3-thiazol-4-ones and (z)-5-ethylidene-1,3-thiazol-4-ones.
Molecules
; 18(5): 5482-97, 2013 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23669632
16.
Three closely related thienyl-substituted 1,4-epoxynaphtho[1,2-b]azepines: hydrogen-bonded assembly in one, two and three dimensions.
Acta Crystallogr C
; 69(Pt 3): 307-12, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23459362
17.
5-Methyl-N-[2-nitro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-amine: a chain of hydrogen-bonded R(2)(2)(6) and R(2)(2)(16) rings.
Acta Crystallogr C
; 69(Pt 2): 172-4, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23377685
18.
(Z)-5-[4-(dimethylamino)benzylidene]-2-(piperidin-1-yl)-1,3-thiazolidin-4(5H)-one.
Acta Crystallogr C
; 69(Pt 1): 74-6, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23282919
19.
Hydrogen-bonded sheet structures in methyl 4-(4-chloroanilino)-3-nitrobenzoate and methyl 1-benzyl-2-(4-chlorophenyl)-1H-benzimidazole-5-carboxylate.
Acta Crystallogr C
; 69(Pt 1): 77-81, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23282920
20.
A chain of π-stacked molecules in 4-(2-chlorophenyl)pyrrolo[1,2-a]quinoxaline and a hydrogen-bonded sheet in (4RS)-4-(1,3-1,3-benzodioxol-6-yl)-4,5-dihydropyrrolo[1,2-a]quinoxaline.
Acta Crystallogr C
; 69(Pt 5): 544-8, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629911