Detalhe da pesquisa
1.
Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine.
Haematologica
; 108(11): 2946-2958, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36951168
2.
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.
Nature
; 511(7507): 90-3, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24870236
3.
Correction: Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation.
J Biol Chem
; 299(10): 105298, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37812844
4.
Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin.
Blood
; 114(2): 257-60, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19433856
5.
Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.
Nat Cell Biol
; 4(12): 963-9, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12447389
6.
A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E.
Haematologica
; 100(1): e7-9, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425688
7.
Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells.
Cancer Res
; 66(3): 1824-32, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16452244
8.
Peripheral and local predictive immune signatures identified in a phase II trial of ipilimumab with carboplatin/paclitaxel in unresectable stage III or stage IV melanoma.
J Immunother Cancer
; 5(1): 83, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29157311
9.
Monitoring Response and Resistance to the Novel Arsenical Darinaparsin in an AML Patient.
Front Pharmacol
; 4: 9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23408639
10.
The Development of Novel Therapies for the Treatment of Acute Myeloid Leukemia (AML).
Cancers (Basel)
; 4(4): 1161-79, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24213503
11.
Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies.
Front Pharmacol
; 2: 59, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22007174
12.
Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.
Clin Cancer Res
; 17(9): 2874-84, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415224
13.
Tyrosine phosphorylation of Grb2: role in prolactin/epidermal growth factor cross talk in mammary epithelial cell growth and differentiation.
Mol Cell Biol
; 29(10): 2505-20, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19273609
14.
Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation.
J Biol Chem
; 283(3): 1293-1307, 2008 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18024957
15.
The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction.
EMBO J
; 24(18): 3247-58, 2005 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16121194