Pesquisa | Portal de Pesquisa da BVS

1.

Birtamimab plus standard of care in light-chain amyloidosis: the phase 3 randomized placebo-controlled VITAL trial.

Gertz, Morie A; Cohen, Adam D; Comenzo, Raymond L; Kastritis, Efstathios; Landau, Heather J; Libby, Edward N; Liedtke, Michaela; Sanchorawala, Vaishali; Schönland, Stefan; Wechalekar, Ashutosh; Zonder, Jeffrey A; Palladini, Giovanni; Walling, Jackie; Guthrie, Spencer; Nie, Christie; Karp, Carol; Jin, Yuying; Kinney, Gene G; Merlini, Giampaolo.

Blood ; 142(14): 1208-1218, 2023 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-37366170

2.

Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis.

Kastritis, Efstathios; Palladini, Giovanni; Minnema, Monique C; Wechalekar, Ashutosh D; Jaccard, Arnaud; Lee, Hans C; Sanchorawala, Vaishali; Gibbs, Simon; Mollee, Peter; Venner, Christopher P; Lu, Jin; Schönland, Stefan; Gatt, Moshe E; Suzuki, Kenshi; Kim, Kihyun; Cibeira, M Teresa; Beksac, Meral; Libby, Edward; Valent, Jason; Hungria, Vania; Wong, Sandy W; Rosenzweig, Michael; Bumma, Naresh; Huart, Antoine; Dimopoulos, Meletios A; Bhutani, Divaya; Waxman, Adam J; Goodman, Stacey A; Zonder, Jeffrey A; Lam, Selay; Song, Kevin; Hansen, Timon; Manier, Salomon; Roeloffzen, Wilfried; Jamroziak, Krzysztof; Kwok, Fiona; Shimazaki, Chihiro; Kim, Jin-Seok; Crusoe, Edvan; Ahmadi, Tahamtan; Tran, NamPhuong; Qin, Xiang; Vasey, Sandra Y; Tromp, Brenda; Schecter, Jordan M; Weiss, Brendan M; Zhuang, Sen H; Vermeulen, Jessica; Merlini, Giampaolo; Comenzo, Raymond L.

N Engl J Med ; 385(1): 46-58, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-34192431

3.

Daratumumab plus bortezomib, cyclophosphamide, and dexamethasone in Asian patients with newly diagnosed AL amyloidosis: subgroup analysis of ANDROMEDA.

Suzuki, Kenshi; Wechalekar, Ashutosh D; Kim, Kihyun; Shimazaki, Chihiro; Kim, Jin Seok; Ikezoe, Takayuki; Min, Chang-Ki; Zhou, Fude; Cai, Zhen; Chen, Xiaonong; Iida, Shinsuke; Katoh, Nagaaki; Fujisaki, Tomoaki; Shin, Ho-Jin; Tran, NamPhuong; Qin, Xiang; Vasey, Sandra Y; Tromp, Brenda; Weiss, Brendan M; Comenzo, Raymond L; Kastritis, Efstathios; Lu, Jin.

Ann Hematol ; 102(4): 863-876, 2023 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-36862168

4.

Quality of life and symptoms among patients with relapsed/refractory AL amyloidosis treated with ixazomib-dexamethasone versus physician's choice.

Sanchorawala, Vaishali; Wechalekar, Ashutosh D; Kim, Kihyun; Schönland, Stefan O; Landau, Heather J; Kwok, Fiona; Suzuki, Kenshi; Dispenzieri, Angela; Merlini, Giampaolo; Comenzo, Raymond L; Cherepanov, Dasha; Hayden, Vanessa C; Kumar, Arun; Labotka, Richard; Faller, Douglas V; Kastritis, Efstathios.

Am J Hematol ; 98(5): 720-729, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36708469

5.

Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma.

Chari, Ajai; Vogl, Dan T; Gavriatopoulou, Maria; Nooka, Ajay K; Yee, Andrew J; Huff, Carol A; Moreau, Philippe; Dingli, David; Cole, Craig; Lonial, Sagar; Dimopoulos, Meletios; Stewart, A Keith; Richter, Joshua; Vij, Ravi; Tuchman, Sascha; Raab, Marc S; Weisel, Katja C; Delforge, Michel; Cornell, Robert F; Kaminetzky, David; Hoffman, James E; Costa, Luciano J; Parker, Terri L; Levy, Moshe; Schreder, Martin; Meuleman, Nathalie; Frenzel, Laurent; Mohty, Mohamad; Choquet, Sylvain; Schiller, Gary; Comenzo, Raymond L; Engelhardt, Monika; Illmer, Thomas; Vlummens, Philip; Doyen, Chantal; Facon, Thierry; Karlin, Lionel; Perrot, Aurore; Podar, Klaus; Kauffman, Michael G; Shacham, Sharon; Li, Lingling; Tang, Shijie; Picklesimer, Carla; Saint-Martin, Jean-Richard; Crochiere, Marsha; Chang, Hua; Parekh, Samir; Landesman, Yosef; Shah, Jatin.

N Engl J Med ; 381(8): 727-738, 2019 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-31433920

6.

Daratumumab plus CyBorD for patients with newly diagnosed AL amyloidosis: safety run-in results of ANDROMEDA.

Palladini, Giovanni; Kastritis, Efstathios; Maurer, Mathew S; Zonder, Jeffrey; Minnema, Monique C; Wechalekar, Ashutosh D; Jaccard, Arnaud; Lee, Hans C; Bumma, Naresh; Kaufman, Jonathan L; Medvedova, Eva; Kovacsovics, Tibor; Rosenzweig, Michael; Sanchorawala, Vaishali; Qin, Xiang; Vasey, Sandra Y; Weiss, Brendan M; Vermeulen, Jessica; Merlini, Giampaolo; Comenzo, Raymond L.

Blood ; 136(1): 71-80, 2020 07 02.

Artigo em Inglês | MEDLINE | ID: mdl-32244252

7.

Outcomes of patients with multiple myeloma harboring chromosome 1q gain/amplification in the era of modern therapy.

Hu, Xiao; Wu, Cherng-Horng; Cowan, Janet M; Comenzo, Raymond L; Varga, Cindy.

Ann Hematol ; 101(2): 369-378, 2022 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-34748077

8.

Health-related quality of life in patients with light chain amyloidosis treated with bortezomib, cyclophosphamide, and dexamethasone ± daratumumab: Results from the ANDROMEDA study.

Sanchorawala, Vaishali; Palladini, Giovanni; Minnema, Monique C; Jaccard, Arnaud; Lee, Hans C; Gibbs, Simon; Mollee, Peter; Venner, Christopher; Lu, Jin; Schönland, Stefan; Gatt, Moshe; Suzuki, Kenshi; Kim, Kihyun; Cibeira, María Teresa; Beksac, Meral; Libby, Edward; Valent, Jason; Hungria, Vania; Wong, Sandy W; Rosenzweig, Michael; Bumma, Naresh; Chauveau, Dominique; Gries, Katharine S; Fastenau, John; Tran, Nam Phuong; Qin, Xiang; Vasey, Sandra Y; Weiss, Brendan M; Vermeulen, Jessica; Ho, Kai Fai; Merlini, Giampaolo; Comenzo, Raymond L; Kastritis, Efstathios; Wechalekar, Ashutosh D.

Am J Hematol ; 97(6): 719-730, 2022 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-35293006

9.

Immunotherapy in AL Amyloidosis.

Zhang, Yifei; Comenzo, Raymond L.

Curr Treat Options Oncol ; 23(7): 1059-1071, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35635625

10.

Implementing structured handoffs to verify operating room blood delivery using a quality academy training program: an interrupted time-series analysis.

Amon, Carly C; Paley, Adina R; Forbes, Judith A; Guzman, Leidy V; Rajwani, Aliysa A; Trzcinka, Agnieszka; Comenzo, Raymond L; Drzymalski, Dan M.

Int J Qual Health Care ; 33(2)2021 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-33825860

11.

Avoiding misdiagnosis: expert consensus recommendations for the suspicion and diagnosis of transthyretin amyloidosis for the general practitioner.

Gertz, Morie; Adams, David; Ando, Yukio; Beirão, João Melo; Bokhari, Sabahat; Coelho, Teresa; Comenzo, Raymond L; Damy, Thibaud; Dorbala, Sharmila; Drachman, Brian M; Fontana, Marianna; Gillmore, Julian D; Grogan, Martha; Hawkins, Philip N; Lousada, Isabelle; Kristen, Arnt V; Ruberg, Frederick L; Suhr, Ole B; Maurer, Mathew S; Nativi-Nicolau, Jose; Quarta, Candida Cristina; Rapezzi, Claudio; Witteles, Ronald; Merlini, Giampaolo.

BMC Fam Pract ; 21(1): 198, 2020 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-32967612

12.

A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases.

Ma, Xun; Zhou, Ping; Kugelmass, Adin; Toskic, Denis; Warner, Melissa; Lee, Lisa; Fogaren, Terry; Godara, Amandeep; Wang, Ming; Li, Yamin; Yang, Liu; Xu, Qiaobing; Comenzo, Raymond L.

Gene Ther ; 26(5): 187-197, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30926963

13.

A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis.

Sanchorawala, Vaishali; Palladini, Giovanni; Kukreti, Vishal; Zonder, Jeffrey A; Cohen, Adam D; Seldin, David C; Dispenzieri, Angela; Jaccard, Arnaud; Schönland, Stefan O; Berg, Deborah; Yang, Huyuan; Gupta, Neeraj; Hui, Ai-Min; Comenzo, Raymond L; Merlini, Giampaolo.

Blood ; 130(5): 597-605, 2017 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-28550039

14.

Beyond the plasma cell: emerging therapies for immunoglobulin light chain amyloidosis.

Weiss, Brendan M; Wong, Sandy W; Comenzo, Raymond L.

Blood ; 127(19): 2275-80, 2016 05 12.

Artigo em Inglês | MEDLINE | ID: mdl-26907632

15.

Commentary on No Monoclonal Protein in a Patient with CRAB Features.

Comenzo, Raymond L.

Clin Chem ; 67(12): 1588-1589, 2021 11 26.

Artigo em Inglês | MEDLINE | ID: mdl-34850844

16.

LECT2 makes the amyloid list.

Comenzo, Raymond L.

Blood ; 123(10): 1436-7, 2014 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-24627547

17.

One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress.

Zhou, Ping; Ma, Xun; Iyer, Lakshmanan; Chaulagain, Chakra; Comenzo, Raymond L.

Blood ; 123(22): 3440-51, 2014 May 29.

Artigo em Inglês | MEDLINE | ID: mdl-24723680

18.

Long-term follow-up from a phase 1/2 study of single-agent bortezomib in relapsed systemic AL amyloidosis.

Reece, Donna E; Hegenbart, Ute; Sanchorawala, Vaishali; Merlini, Giampaolo; Palladini, Giovanni; Bladé, Joan; Fermand, Jean-Paul; Hassoun, Hani; Heffner, Leonard; Kukreti, Vishal; Vescio, Robert A; Pei, Lixia; Enny, Christopher; Esseltine, Dixie-Lee; van de Velde, Helgi; Cakana, Andrew; Comenzo, Raymond L.

Blood ; 124(16): 2498-506, 2014 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-25202139

19.

Involved free light chains <10 mg/L with treatment predict better outcomes in systemic light-chain amyloidosis.

Godara, Amandeep; Toskic, Denis; Albanese, Jack; Rosenthal, Benjamin; Siddiqui, Nauman S; Kugelmass, Adin; Zhou, Ping; Fogaren, Teresa; Varga, Cindy; Landau, Heather J; Comenzo, Raymond L.

Am J Hematol ; 96(1): E20-E23, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33068021

20.

Beyond NEOD001 for systemic light-chain amyloidosis.

Varga, Cindy; Lentzsch, Suzanne; Comenzo, Raymond L.

Blood ; 132(18): 1992-1993, 2018 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-30242086

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