Detalhe da pesquisa
1.
Type-I-interferon-responsive microglia shape cortical development and behavior.
Cell
; 187(8): 1936-1954.e24, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490196
2.
Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aß prions.
Proc Natl Acad Sci U S A
; 120(13): e2220984120, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36952379
3.
EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains.
Proc Natl Acad Sci U S A
; 120(12): e2300769120, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927157
4.
Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.
Proc Natl Acad Sci U S A
; 119(6)2022 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35115402
5.
Aß and tau prions feature in the neuropathogenesis of Down syndrome.
Proc Natl Acad Sci U S A
; 119(46): e2212954119, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343257
6.
Soluble TREM2 inhibits secondary nucleation of Aß fibrillization and enhances cellular uptake of fibrillar Aß.
Proc Natl Acad Sci U S A
; 119(5)2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082148
7.
Amyloid ß Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer's Disease.
J Proteome Res
; 22(11): 3475-3488, 2023 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37847596
8.
Structural heterogeneity and intersubject variability of Aß in familial and sporadic Alzheimer's disease.
Proc Natl Acad Sci U S A
; 115(4): E782-E791, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311311
9.
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Proc Natl Acad Sci U S A
; 114(51): E11029-E11036, 2017 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29203673
10.
Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.
J Autoimmun
; 101: 56-69, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010726
11.
Aß propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease.
Neurobiol Dis
; 109(Pt B): 191-200, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28359847
12.
Distinct synthetic Aß prion strains producing different amyloid deposits in bigenic mice.
Proc Natl Acad Sci U S A
; 111(28): 10329-34, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982137
13.
Serial propagation of distinct strains of Aß prions from Alzheimer's disease patients.
Proc Natl Acad Sci U S A
; 111(28): 10323-8, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982139
14.
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
J Pharmacol Exp Ther
; 358(3): 537-47, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27317802
15.
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
J Pharmacol Exp Ther
; 355(1): 2-12, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26224882
16.
Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold.
bioRxiv
; 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38617229
17.
Total Chemical Synthesis of Glycosylated TREM2 Ectodomain.
ACS Chem Neurosci
; 14(11): 2243-2251, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37235776
18.
Aß and Tau Prions Causing Alzheimer's Disease.
Methods Mol Biol
; 2561: 293-337, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399277
19.
EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains.
bioRxiv
; 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778268
20.
De novo Design of Peptides that Bind Specific Conformers of α-Synuclein.
bioRxiv
; 2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014268