Detalhe da pesquisa
1.
Structural and Functional Determinants of AC8 Trafficking, Targeting and Responsiveness in Lipid Raft Microdomains.
J Membr Biol
; 252(2-3): 159-172, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30746562
2.
Adenylate cyclase-centred microdomains.
Biochem J
; 462(2): 199-213, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25102028
3.
TRPC1 contributes to the Ca2+-dependent regulation of adenylate cyclases.
Biochem J
; 464(1): 73-84, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25133583
4.
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex.
EMBO J
; 29(16): 2772-87, 2010 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664520
5.
Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu.
J Cell Sci
; 125(Pt 4): 869-86, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399809
6.
A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.
J Cell Sci
; 125(Pt 23): 5850-9, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22976297
7.
AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex.
Biochem J
; 455(1): 47-56, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23889134
8.
Structural insights into calmodulin/adenylyl cyclase 8 interaction.
Anal Bioanal Chem
; 405(29): 9333-42, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24071896
9.
Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gßγ subunits exert opposing effects depending on the G-protein source.
Biochem J
; 447(3): 393-405, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22906005
10.
Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8.
Biochemistry
; 51(40): 7917-29, 2012 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22971080
11.
Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8.
J Biol Chem
; 286(38): 32962-75, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21771783
12.
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
J Biol Chem
; 286(11): 9079-96, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177871
13.
Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase.
J Cell Sci
; 123(Pt 1): 107-17, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016071
14.
Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.
J Cell Sci
; 123(Pt 1): 95-106, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016070
15.
cAMP measurements with FRET-based sensors in excitable cells.
Biochem Soc Trans
; 40(1): 179-83, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22260686
16.
AKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systems.
J Biol Chem
; 285(26): 20328-42, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20410303
17.
Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8.
J Biol Chem
; 290(21): 13041, 2015 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002951
18.
Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity.
Am J Physiol Lung Cell Mol Physiol
; 301(1): L117-24, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478251
19.
Live-cell imaging of cAMP dynamics.
Nat Methods
; 5(1): 29-36, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18165805
20.
AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.
Function (Oxf)
; 2(5): zqab036, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458850