Detalhe da pesquisa
1.
Activation of class 1 integron integrase is promoted in the intestinal environment.
PLoS Genet
; 18(4): e1010177, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482826
2.
Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling.
Antimicrob Agents Chemother
; 67(10): e0048023, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695298
3.
Pharmacokinetic and pharmacodynamic properties of polymyxin B in Escherichia coli and Klebsiella pneumoniae murine infection models.
J Antimicrob Chemother
; 78(3): 832-839, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36718051
4.
A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro.
Antimicrob Agents Chemother
; 66(1): e0178921, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780268
5.
Population pharmacokinetic/pharmacodynamic study suggests continuous infusion of ceftaroline daily dose in ventilated critical care patients with early-onset pneumonia and augmented renal clearance.
J Antimicrob Chemother
; 77(11): 3173-3179, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36059138
6.
Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics.
Pharm Res
; 39(12): 3267-3277, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36163408
7.
Comparative pharmacokinetics of the three echinocandins in ICU patients.
J Antimicrob Chemother
; 75(10): 2969-2976, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32696036
8.
Pulmonary Pharmacokinetics of Oseltamivir Carboxylate in Rats after Nebulization or Intravenous Administration of Its Prodrug, Oseltamivir Phosphate.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962337
9.
Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31061149
10.
Cerebrospinal fluid pharmacokinetics of ceftaroline in neurosurgical patients with an external ventricular drain.
J Antimicrob Chemother
; 74(3): 675-681, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30535190
11.
Reassessing the dosing of cefoxitin prophylaxis during major abdominal surgery: insights from microdialysis and population pharmacokinetic modelling.
J Antimicrob Chemother
; 74(7): 1975-1983, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31220258
12.
Population pharmacokinetics of daptomycin in critically ill patients with various degrees of renal impairment.
J Antimicrob Chemother
; 74(1): 117-125, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30295740
13.
Pharmacokinetics of Polymyxins in Animals.
Adv Exp Med Biol
; 1145: 89-103, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31364073
14.
Microdialysis Study of Aztreonam-Avibactam Distribution in Peritoneal Fluid and Muscle of Rats with or without Experimental Peritonitis.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012776
15.
Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082284
16.
Pharmacokinetics of Tedizolid in an Obese Patient after Bariatric Surgery.
Antimicrob Agents Chemother
; 62(4)2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378714
17.
Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients.
J Antimicrob Chemother
; 73(10): 2830-2837, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947799
18.
A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion.
Pharm Res
; 35(5): 92, 2018 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29532176
19.
Pharmacokinetics of nebulized colistin methanesulfonate in critically ill patients.
J Antimicrob Chemother
; 72(9): 2607-2612, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575278
20.
Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling.
PLoS Comput Biol
; 12(3): e1004782, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26967893