Detalhe da pesquisa
1.
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
Mol Cell
; 82(13): 2385-2400.e9, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594856
2.
A druggable copper-signalling pathway that drives inflammation.
Nature
; 617(7960): 386-394, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37100912
3.
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
PLoS Pathog
; 19(8): e1011559, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37619220
4.
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa.
PLoS Pathog
; 18(7): e1010305, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849616
5.
Mycobacteria-host interactions in human bronchiolar airway organoids.
Mol Microbiol
; 117(3): 682-692, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605588
6.
Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
PLoS Pathog
; 17(9): e1009927, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516571
7.
A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt+ Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis.
J Immunol
; 207(7): 1857-1870, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34479945
8.
Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation.
PLoS Pathog
; 16(10): e1008929, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33002063
9.
Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model.
Int J Mol Sci
; 23(21)2022 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362409
10.
C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.
Proc Natl Acad Sci U S A
; 114(4): E540-E549, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069953
11.
Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells.
Mem Inst Oswaldo Cruz
; 114: e190102, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31411311
12.
Comorbid medical conditions are a key factor to understand the relationship between psychiatric disorders and COVID-19-related mortality: Results from 49,089 COVID-19 inpatients.
Mol Psychiatry
; 27(3): 1278-1280, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837060
13.
Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis.
Mem Inst Oswaldo Cruz
; 113(4): e170326, 2018 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29513874
14.
Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms.
Mol Psychiatry
; 26(12): 7098-7099, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385600
15.
Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.
Circulation
; 132(6): 490-501, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068045
16.
Molecular and cellular profiles of the resolution phase in a damage-associated molecular pattern (DAMP)-mediated peritonitis model and revelation of leukocyte persistence in peritoneal tissues.
FASEB J
; 29(5): 1914-29, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25609430
17.
Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function.
J Biol Chem
; 289(11): 7897-906, 2014 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24482227
18.
An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages.
Immunol Cell Biol
; 92(8): 699-708, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24890643
19.
Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors.
FASEB J
; 27(9): 3608-18, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23742809
20.
Fluoxetine and Sertraline Potently Neutralize the Replication of Distinct SARS-CoV-2 Variants.
Viruses
; 16(4)2024 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675888