1.
Cell
; 161(2): 418-418.e1, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25860614
RESUMO
The fundamental unit of DNA replication, the replicon, is governed by a cis-acting replicator sequence and a trans-activating initiator factor. Despite the increased size and complexity of eukaryotic genomes, eukaryotic DNA replication continues to be guided by the fundamental principles and concepts established in the replicon model.