Detalhe da pesquisa
1.
Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants.
Proc Natl Acad Sci U S A
; 117(32): 18924-18933, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32753378
2.
Analysis of overlapping genetic association in type 1 and type 2 diabetes.
Diabetologia
; 64(6): 1342-1347, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830302
3.
Genetics of the human face: Identification of large-effect single gene variants.
Proc Natl Acad Sci U S A
; 115(4): E676-E685, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301965
4.
Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing.
J Theor Biol
; 489: 110153, 2020 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935413
5.
Statistical aspects of evolution under natural selection, with implications for the advantage of sexual reproduction.
J Theor Biol
; 431: 79-86, 2017 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28779948
6.
Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach.
Nat Commun
; 13(1): 2337, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484151
7.
Genetic regulation of RNA splicing in human pancreatic islets.
Genome Biol
; 23(1): 196, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36109769
8.
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Nat Genet
; 53(7): 962-971, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34127860
9.
Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic ß-Cells.
Diabetes Care
; 43(1): 169-177, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558544
10.
Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression.
Front Immunol
; 10: 2606, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31781109
11.
Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancer.
Cancer Epidemiol
; 37(3): 324-9, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23375517
12.
REGENT: a risk assessment and classification algorithm for genetic and environmental factors.
Eur J Hum Genet
; 21(1): 109-11, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22669417
13.
Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs.
Eur J Hum Genet
; 20(12): 1283-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22739346
14.
Genes predict village of origin in rural Europe.
Eur J Hum Genet
; 18(11): 1269-70, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20571506