Detalhe da pesquisa
1.
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 560(7717): 192-197, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046105
2.
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 619(7970): E48, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402863
3.
Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds.
Drug Metab Dispos
; 49(2): 169-178, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33239335
4.
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.
RSC Med Chem
; 11(10): 1168-1177, 2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479621
5.
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.
J Med Chem
; 62(3): 1180-1202, 2019 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570265
6.
Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656).
J Med Chem
; 60(19): 8011-8026, 2017 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953378
7.
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
J Med Chem
; 60(17): 7284-7299, 2017 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28844141
8.
Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.
PLoS Negl Trop Dis
; 8(10): e3253, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25340575