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1.
Sensors (Basel) ; 24(19)2024 Sep 29.
Artigo em Inglês | MEDLINE | ID: mdl-39409365

RESUMO

Telephysiotherapy has emerged as a vital solution for delivering remote healthcare, particularly in response to global challenges such as the COVID-19 pandemic. This study seeks to enhance telephysiotherapy by developing a system capable of accurately classifying physiotherapeutic exercises using PoseNet, a state-of-the-art pose estimation model. A dataset was collected from 49 participants (35 males, 14 females) performing seven distinct exercises, with twelve anatomical landmarks then extracted using the Google MediaPipe library. Each landmark was represented by four features, which were used for classification. The core challenge addressed in this research involves ensuring accurate and real-time exercise classification across diverse body morphologies and exercise types. Several tree-based classifiers, including Random Forest, Extra Tree Classifier, XGBoost, LightGBM, and Hist Gradient Boosting, were employed. Furthermore, two novel ensemble models called RandomLightHist Fusion and StackedXLightRF are proposed to enhance classification accuracy. The RandomLightHist Fusion model achieved superior accuracy of 99.6%, demonstrating the system's robustness and effectiveness. This innovation offers a practical solution for providing real-time feedback in telephysiotherapy, with potential to improve patient outcomes through accurate monitoring and assessment of exercise performance.


Assuntos
COVID-19 , Humanos , Feminino , Masculino , SARS-CoV-2 , Exercício Físico/fisiologia , Braço/fisiologia , Telemedicina , Modalidades de Fisioterapia , Algoritmos , Adulto , Pandemias
2.
Sensors (Basel) ; 24(17)2024 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-39275444

RESUMO

Physiotherapy plays a crucial role in the rehabilitation of damaged or defective organs due to injuries or illnesses, often requiring long-term supervision by a physiotherapist in clinical settings or at home. AI-based support systems have been developed to enhance the precision and effectiveness of physiotherapy, particularly during the COVID-19 pandemic. These systems, which include game-based or tele-rehabilitation monitoring using camera-based optical systems like Vicon and Microsoft Kinect, face challenges such as privacy concerns, occlusion, and sensitivity to environmental light. Non-optical sensor alternatives, such as Inertial Movement Units (IMUs), Wi-Fi, ultrasound sensors, and ultrawide band (UWB) radar, have emerged to address these issues. Although IMUs are portable and cost-effective, they suffer from disadvantages like drift over time, limited range, and susceptibility to magnetic interference. In this study, a single UWB radar was utilized to recognize five therapeutic exercises related to the upper limb, performed by 34 male volunteers in a real environment. A novel feature fusion approach was developed to extract distinguishing features for these exercises. Various machine learning methods were applied, with the EnsembleRRGraBoost ensemble method achieving the highest recognition accuracy of 99.45%. The performance of the EnsembleRRGraBoost model was further validated using five-fold cross-validation, maintaining its high accuracy.


Assuntos
COVID-19 , Aprendizado de Máquina , Radar , Humanos , Masculino , SARS-CoV-2 , Terapia por Exercício/métodos , Algoritmos , Adulto
3.
Sensors (Basel) ; 23(15)2023 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-37571620

RESUMO

With a view of the post-COVID-19 world and probable future pandemics, this paper presents an Internet of Things (IoT)-based automated healthcare diagnosis model that employs a mixed approach using data augmentation, transfer learning, and deep learning techniques and does not require physical interaction between the patient and physician. Through a user-friendly graphic user interface and availability of suitable computing power on smart devices, the embedded artificial intelligence allows the proposed model to be effectively used by a layperson without the need for a dental expert by indicating any issues with the teeth and subsequent treatment options. The proposed method involves multiple processes, including data acquisition using IoT devices, data preprocessing, deep learning-based feature extraction, and classification through an unsupervised neural network. The dataset contains multiple periapical X-rays of five different types of lesions obtained through an IoT device mounted within the mouth guard. A pretrained AlexNet, a fast GPU implementation of a convolutional neural network (CNN), is fine-tuned using data augmentation and transfer learning and employed to extract the suitable feature set. The data augmentation avoids overtraining, whereas accuracy is improved by transfer learning. Later, support vector machine (SVM) and the K-nearest neighbors (KNN) classifiers are trained for lesion classification. It was found that the proposed automated model based on the AlexNet extraction mechanism followed by the SVM classifier achieved an accuracy of 98%, showing the effectiveness of the presented approach.


Assuntos
COVID-19 , Aprendizado Profundo , Internet das Coisas , Humanos , Inteligência Artificial , Análise por Conglomerados
4.
Sensors (Basel) ; 23(15)2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37571624

RESUMO

Cricket has a massive global following and is ranked as the second most popular sport globally, with an estimated 2.5 billion fans. Batting requires quick decisions based on ball speed, trajectory, fielder positions, etc. Recently, computer vision and machine learning techniques have gained attention as potential tools to predict cricket strokes played by batters. This study presents a cutting-edge approach to predicting batsman strokes using computer vision and machine learning. The study analyzes eight strokes: pull, cut, cover drive, straight drive, backfoot punch, on drive, flick, and sweep. The study uses the MediaPipe library to extract features from videos and several machine learning and deep learning algorithms, including random forest (RF), support vector machine, k-nearest neighbors, decision tree, linear regression, and long short-term memory to predict the strokes. The study achieves an outstanding accuracy of 99.77% using the RF algorithm, outperforming the other algorithms used in the study. The k-fold validation of the RF model is 95.0% with a standard deviation of 0.07, highlighting the potential of computer vision and machine learning techniques for predicting batsman strokes in cricket. The study's results could help improve coaching techniques and enhance batsmen's performance in cricket, ultimately improving the game's overall quality.


Assuntos
Críquete , Humanos , Algoritmos , Aprendizado de Máquina , Máquina de Vetores de Suporte
5.
Sensors (Basel) ; 23(12)2023 Jun 06.
Artigo em Inglês | MEDLINE | ID: mdl-37420546

RESUMO

Recent developments in quantum computing have shed light on the shortcomings of the conventional public cryptosystem. Even while Shor's algorithm cannot yet be implemented on quantum computers, it indicates that asymmetric key encryption will not be practicable or secure in the near future. The National Institute of Standards and Technology (NIST) has started looking for a post-quantum encryption algorithm that is resistant to the development of future quantum computers as a response to this security concern. The current focus is on standardizing asymmetric cryptography that should be impenetrable by a quantum computer. This has become increasingly important in recent years. Currently, the process of standardizing asymmetric cryptography is coming very close to being finished. This study evaluated the performance of two post-quantum cryptography (PQC) algorithms, both of which were selected as NIST fourth-round finalists. The research assessed the key generation, encapsulation, and decapsulation operations, providing insights into their efficiency and suitability for real-world applications. Further research and standardization efforts are required to enable secure and efficient post-quantum encryption. When selecting appropriate post-quantum encryption algorithms for specific applications, factors such as security levels, performance requirements, key sizes, and platform compatibility should be taken into account. This paper provides helpful insight for post-quantum cryptography researchers and practitioners, assisting in the decision-making process for selecting appropriate algorithms to protect confidential data in the age of quantum computing.


Assuntos
Segurança Computacional , Metodologias Computacionais , Teoria Quântica , Algoritmos , Computadores
6.
Sensors (Basel) ; 23(14)2023 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-37514673

RESUMO

An Internet of Things (IoT) network is prone to many ways of threatening individuals. IoT sensors are lightweight, lack complicated security protocols, and face threats to privacy and confidentiality. Hackers can attack the IoT network and access personal information and confidential data for blackmailing, and negatively manipulate data. This study aims to propose an IoT threat protection system (IoTTPS) to protect the IoT network from threats using an ensemble model RKSVM, comprising a random forest (RF), K nearest neighbor (KNN), and support vector machine (SVM) model. The software-defined networks (SDN)-based IoT network datasets such as KDD cup 99, NSL-KDD, and CICIDS are used for threat detection based on machine learning. The experimental phase is conducted by using a decision tree (DT), logistic regression (LR), Naive Bayes (NB), RF, SVM, gradient boosting machine (GBM), KNN, and the proposed ensemble RKSVM model. Furthermore, performance is optimized by adding a grid search hyperparameter optimization technique with K-Fold cross-validation. As well as the NSL-KDD dataset, two other datasets, KDD and CIC-IDS 2017, are used to validate the performance. Classification accuracies of 99.7%, 99.3%, 99.7%, and 97.8% are obtained for DoS, Probe, U2R, and R2L attacks using the proposed ensemble RKSVM model using grid search and cross-fold validation. Experimental results demonstrate the superior performance of the proposed model for IoT threat detection.

7.
Sensors (Basel) ; 23(11)2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-37299993

RESUMO

Internet of Things (IoT) has made significant strides in energy management systems recently. Due to the continually increasing cost of energy, supply-demand disparities, and rising carbon footprints, the need for smart homes for monitoring, managing, and conserving energy has increased. In IoT-based systems, device data are delivered to the network edge before being stored in the fog or cloud for further transactions. This raises worries about the data's security, privacy, and veracity. It is vital to monitor who accesses and updates this information to protect IoT end-users linked to IoT devices. Smart meters are installed in smart homes and are susceptible to numerous cyber attacks. Access to IoT devices and related data must be secured to prevent misuse and protect IoT users' privacy. The purpose of this research was to design a blockchain-based edge computing method for securing the smart home system, in conjunction with machine learning techniques, in order to construct a secure smart home system with energy usage prediction and user profiling. The research proposes a blockchain-based smart home system that can continuously monitor IoT-enabled smart home appliances such as smart microwaves, dishwashers, furnaces, and refrigerators, among others. An approach based on machine learning was utilized to train the auto-regressive integrated moving average (ARIMA) model for energy usage prediction, which is provided in the user's wallet, to estimate energy consumption and maintain user profiles. The model was tested using the moving average statistical model, the ARIMA model, and the deep-learning-based long short-term memory (LSTM) model on a dataset of smart-home-based energy usage under changing weather conditions. The findings of the analysis reveal that the LSTM model accurately forecasts the energy usage of smart homes.


Assuntos
Blockchain , Internet das Coisas , Aprendizado de Máquina , Memória de Longo Prazo , Micro-Ondas
8.
Sensors (Basel) ; 23(13)2023 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-37447939

RESUMO

A new artificial intelligence-based approach is proposed by developing a deep learning (DL) model for identifying the people who violate the face mask protocol in public places. To achieve this goal, a private dataset was created, including different face images with and without masks. The proposed model was trained to detect face masks from real-time surveillance videos. The proposed face mask detection (FMDNet) model achieved a promising detection of 99.0% in terms of accuracy for identifying violations (no face mask) in public places. The model presented a better detection capability compared to other recent DL models such as FSA-Net, MobileNet V2, and ResNet by 24.03%, 5.0%, and 24.10%, respectively. Meanwhile, the model is lightweight and had a confidence score of 99.0% in a resource-constrained environment. The model can perform the detection task in real-time environments at 41.72 frames per second (FPS). Thus, the developed model can be applicable and useful for governments to maintain the rules of the SOP protocol.


Assuntos
COVID-19 , Máscaras , Humanos , Inteligência Artificial , Pandemias , Equipamento de Proteção Individual
9.
Sensors (Basel) ; 22(22)2022 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-36433511

RESUMO

This paper presents the design, development, and testing of an IoT-enabled smart stick for visually impaired people to navigate the outside environment with the ability to detect and warn about obstacles. The proposed design employs ultrasonic sensors for obstacle detection, a water sensor for sensing the puddles and wet surfaces in the user's path, and a high-definition video camera integrated with object recognition. Furthermore, the user is signaled about various hindrances and objects using voice feedback through earphones after accurately detecting and identifying objects. The proposed smart stick has two modes; one uses ultrasonic sensors for detection and feedback through vibration motors to inform about the direction of the obstacle, and the second mode is the detection and recognition of obstacles and providing voice feedback. The proposed system allows for switching between the two modes depending on the environment and personal preference. Moreover, the latitude/longitude values of the user are captured and uploaded to the IoT platform for effective tracking via global positioning system (GPS)/global system for mobile communication (GSM) modules, which enable the live location of the user/stick to be monitored on the IoT dashboard. A panic button is also provided for emergency assistance by generating a request signal in the form of an SMS containing a Google maps link generated with latitude and longitude coordinates and sent through an IoT-enabled environment. The smart stick has been designed to be lightweight, waterproof, size adjustable, and has long battery life. The overall design ensures energy efficiency, portability, stability, ease of access, and robust features.


Assuntos
Tecnologia Assistiva , Auxiliares Sensoriais , Pessoas com Deficiência Visual , Humanos , Desenho de Equipamento , Bengala
10.
Sensors (Basel) ; 22(19)2022 Oct 10.
Artigo em Inglês | MEDLINE | ID: mdl-36236791

RESUMO

Building energy consumption prediction has become an important research problem within the context of sustainable homes and smart cities. Data-driven approaches have been regarded as the most suitable for integration into smart houses. With the wide deployment of IoT sensors, the data generated from these sensors can be used for modeling and forecasting energy consumption patterns. Existing studies lag in prediction accuracy and various attributes of buildings are not very well studied. This study follows a data-driven approach in this regard. The novelty of the paper lies in the fact that an ensemble model is proposed, which provides higher performance regarding cooling and heating load prediction. Moreover, the influence of different features on heating and cooling load is investigated. Experiments are performed by considering different features such as glazing area, orientation, height, relative compactness, roof area, surface area, and wall area. Results indicate that relative compactness, surface area, and wall area play a significant role in selecting the appropriate cooling and heating load for a building. The proposed model achieves 0.999 R2 for heating load prediction and 0.997 R2 for cooling load prediction, which is superior to existing state-of-the-art models. The precise prediction of heating and cooling load, can help engineers design energy-efficient buildings, especially in the context of future smart homes.

11.
Appl Soft Comput ; 126: 109319, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36034154

RESUMO

Chest radiographs are widely used in the medical domain and at present, chest X-radiation particularly plays an important role in the diagnosis of medical conditions such as pneumonia and COVID-19 disease. The recent developments of deep learning techniques led to a promising performance in medical image classification and prediction tasks. With the availability of chest X-ray datasets and emerging trends in data engineering techniques, there is a growth in recent related publications. Recently, there have been only a few survey papers that addressed chest X-ray classification using deep learning techniques. However, they lack the analysis of the trends of recent studies. This systematic review paper explores and provides a comprehensive analysis of the related studies that have used deep learning techniques to analyze chest X-ray images. We present the state-of-the-art deep learning based pneumonia and COVID-19 detection solutions, trends in recent studies, publicly available datasets, guidance to follow a deep learning process, challenges and potential future research directions in this domain. The discoveries and the conclusions of the reviewed work have been organized in a way that researchers and developers working in the same domain can use this work to support them in taking decisions on their research.

13.
PLoS One ; 19(3): e0300725, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38547173

RESUMO

Named Entity Recognition (NER) is a natural language processing task that has been widely explored for different languages in the recent decade but is still an under-researched area for the Urdu language due to its rich morphology and language complexities. Existing state-of-the-art studies on Urdu NER use various deep-learning approaches through automatic feature selection using word embeddings. This paper presents a deep learning approach for Urdu NER that harnesses FastText and Floret word embeddings to capture the contextual information of words by considering the surrounding context of words for improved feature extraction. The pre-trained FastText and Floret word embeddings are publicly available for Urdu language which are utilized to generate feature vectors of four benchmark Urdu language datasets. These features are then used as input to train various combinations of Long Short-Term Memory (LSTM), Bidirectional LSTM (BiLSTM), Gated Recurrent Unit (GRU), CRF, and deep learning models. The results show that our proposed approach significantly outperforms existing state-of-the-art studies on Urdu NER, achieving an F-score of up to 0.98 when using BiLSTM+GRU with Floret embeddings. Error analysis shows a low classification error rate ranging from 1.24% to 3.63% across various datasets showing the robustness of the proposed approach. The performance comparison shows that the proposed approach significantly outperforms similar existing studies.


Assuntos
Aprendizado Profundo , Nomes , Idioma , Processamento de Linguagem Natural , Benchmarking
14.
PLoS One ; 19(3): e0298582, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38466691

RESUMO

With the outbreak of the COVID-19 pandemic, social isolation and quarantine have become commonplace across the world. IoT health monitoring solutions eliminate the need for regular doctor visits and interactions among patients and medical personnel. Many patients in wards or intensive care units require continuous monitoring of their health. Continuous patient monitoring is a hectic practice in hospitals with limited staff; in a pandemic situation like COVID-19, it becomes much more difficult practice when hospitals are working at full capacity and there is still a risk of medical workers being infected. In this study, we propose an Internet of Things (IoT)-based patient health monitoring system that collects real-time data on important health indicators such as pulse rate, blood oxygen saturation, and body temperature but can be expanded to include more parameters. Our system is comprised of a hardware component that collects and transmits data from sensors to a cloud-based storage system, where it can be accessed and analyzed by healthcare specialists. The ESP-32 microcontroller interfaces with the multiple sensors and wirelessly transmits the collected data to the cloud storage system. A pulse oximeter is utilized in our system to measure blood oxygen saturation and body temperature, as well as a heart rate monitor to measure pulse rate. A web-based interface is also implemented, allowing healthcare practitioners to access and visualize the collected data in real-time, making remote patient monitoring easier. Overall, our IoT-based patient health monitoring system represents a significant advancement in remote patient monitoring, allowing healthcare practitioners to access real-time data on important health metrics and detect potential health issues before they escalate.


Assuntos
Computação em Nuvem , Internet das Coisas , Humanos , Pandemias , Monitorização Fisiológica , Armazenamento e Recuperação da Informação
15.
PLoS One ; 19(7): e0304774, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38985779

RESUMO

The IoT (Internet of Things) has played a promising role in e-healthcare applications during the last decade. Medical sensors record a variety of data and transmit them over the IoT network to facilitate remote patient monitoring. When a patient visits a hospital he may need to connect or disconnect medical devices from the medical healthcare system frequently. Also, multiple entities (e.g., doctors, medical staff, etc.) need access to patient data and require distinct sets of patient data. As a result of the dynamic nature of medical devices, medical users require frequent access to data, which raises complex security concerns. Granting access to a whole set of data creates privacy issues. Also, each of these medical user need to grant access rights to a specific set of medical data, which is quite a tedious task. In order to provide role-based access to medical users, this study proposes a blockchain-based framework for authenticating multiple entities based on the trust domain to reduce the administrative burden. This study is further validated by simulation on the infura blockchain using solidity and Python. The results demonstrate that role-based authorization and multi-entities authentication have been implemented and the owner of medical data can control access rights at any time and grant medical users easy access to a set of data in a healthcare system. The system has minimal latency compared to existing blockchain systems that lack multi-entity authentication and role-based authorization.


Assuntos
Blockchain , Segurança Computacional , Humanos , Internet das Coisas , Confidencialidade , Telemedicina
16.
PeerJ Comput Sci ; 10: e1697, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38259896

RESUMO

Public concern regarding health systems has experienced a rapid surge during the last two years due to the COVID-19 outbreak. Accordingly, medical professionals and health-related institutions reach out to patients and seek feedback to analyze, monitor, and uplift medical services. Such views and perceptions are often shared on social media platforms like Facebook, Instagram, Twitter, etc. Twitter is the most popular and commonly used by the researcher as an online platform for instant access to real-time news, opinions, and discussion. Its trending hashtags (#) and viral content make it an ideal hub for monitoring public opinion on a variety of topics. The tweets are extracted using three hashtags #healthcare, #healthcare services, and #medical facilities. Also, location and tweet sentiment analysis are considered in this study. Several recent studies deployed Twitter datasets using ML and DL models, but the results show lower accuracy. In addition, the studies did not perform extensive comparative analysis and lack validation. This study addresses two research questions: first, what are the sentiments of people toward medical services worldwide? and second, how effective are the machine learning and deep learning approaches for the classification of sentiment on healthcare tweets? Experiments are performed using several well-known machine learning models including support vector machine, logistic regression, Gaussian naive Bayes, extra tree classifier, k nearest neighbor, random forest, decision tree, and AdaBoost. In addition, this study proposes a transfer learning-based LSTM-ETC model that effectively predicts the customer's satisfaction level from the healthcare dataset. Results indicate that despite the best performance by the ETC model with an 0.88 accuracy score, the proposed model outperforms with a 0.95 accuracy score. Predominantly, the people are happy about the provided medical services as the ratio of the positive sentiments is substantially higher than the negative sentiments. The sentiments, either positive or negative, play a crucial role in making important decisions through customer feedback and enhancing quality.

17.
Digit Health ; 10: 20552076241277185, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39502490

RESUMO

Objective: Epileptic seizures are neurological events that pose significant risks of physical injuries characterized by sudden, abnormal bursts of electrical activity in the brain, often leading to loss of consciousness and uncontrolled movements. Early seizure detection is essential for timely treatments and better patient outcomes. To address this critical issue, there is a need for an advanced artificial intelligence approach for the early detection of epileptic seizure disorder. Methods: This study primarily focuses on designing a novel ensemble approach to perform early detection of epileptic seizure disease with high performance. A novel ensemble approach consisting of a fast, independent component analysis random forest (FIR) and prediction probability is proposed, which uses electroencephalography (EEG) data to investigate the efficacy of the proposed approach for early detection of epileptic seizures. The FIR model extracts independent components and class prediction probability features, creating a new feature set. The proposed model combined integrated component analysis (ICA) with predicting probability to enhance seizure recognition accuracy scores. Extensive experimental evaluations demonstrate that FIR assists machine learning models to obtain superior results compared to original features. Results: The research gap is addressed using combined features to improve the performance of epileptic seizure detection compared to a single feature set. In particular, the ensemble model FIR with support vector machine (FIR + SVM) outperforms other methods, achieving an accuracy of 98.4% for epileptic seizure detection. Conclusions: The proposed FIR has the potential for early diagnosis of epileptic seizures and can significantly help the medical industry with enhanced detection and timely interventions.

18.
PLoS One ; 19(1): e0295036, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38206967

RESUMO

The wheat crop that fulfills 35% of human food demand is facing several problems due to a lack of transparency, security, reliability, and traceability in the existing agriculture supply chain. Many systems have been developed for the agriculture supply chain to overcome such issues, however, monopolistic centralized control is the biggest hurdle to realizing the use of such systems. It has eventually gained consumers' trust in branded products and rejected other products due to the lack of traceable supply chain information. This study proposes a blockchain-based framework for supply chain traceability which provides trustable, transparent, secure, and reliable services for the wheat crop. A crypto token called wheat coin (WC) has been introduced to keep track of transactions among the stakeholders of the wheat supply chain. Moreover, an initial coin offering (ICO) of WC, crypto wallets, and an economic model are proposed. Furthermore, a smart contract-based transaction system has been devised for the transparency of wheat crop transactions and conversion of WC to fiat and vice versa. We have developed the interplanetary file system (IPFS) to improve data availability, security, and transparency which stores encrypted private data of farmers, businesses, and merchants. Lastly, the results of the experiments show that the proposed framework shows better performance as compared to previous crop supply chain solutions in terms of latency to add-blocks, per-minute transactions, average gas charge for the transaction, and transaction verification time. Performance analysis with Bitcoin and Ethereum shows the superior performance of the proposed system.


Assuntos
Blockchain , Cryptococcus neoformans , Criptosporidiose , Humanos , Triticum , Reprodutibilidade dos Testes , Agricultura , Comércio
19.
Front Pharmacol ; 15: 1331622, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38410133

RESUMO

Objective: This study aims to determine the efficacy of the Acacia arabica (Lam.) Willd. and Cinnamomum camphora (L.) J. Presl. vaginal suppository in addressing heavy menstrual bleeding (HMB) and their impact on participants' health-related quality of life (HRQoL) analyzed using machine learning algorithms. Method: A total of 62 participants were enrolled in a double-dummy, single-center study. They were randomly assigned to either the suppository group (SG), receiving a formulation prepared with Acacia arabica gum (Gond Babul) and camphor from Cinnamomum camphora (Kafoor) through two vaginal suppositories (each weighing 3,500 mg) for 7 days at bedtime along with oral placebo capsules, or the tranexamic group (TG), receiving oral tranexamic acid (500 mg) twice a day for 5 days and two placebo vaginal suppositories during menstruation at bedtime for three consecutive menstrual cycles. The primary outcome was the pictorial blood loss assessment chart (PBLAC) for HMB, and secondary outcomes included hemoglobin level and SF-36 HRQoL questionnaire scores. Additionally, machine learning algorithms such as k-nearest neighbor (KNN), AdaBoost (AB), naive Bayes (NB), and random forest (RF) classifiers were employed for analysis. Results: In the SG and TG, the mean PBLAC score decreased from 635.322 ± 504.23 to 67.70 ± 22.37 and 512.93 ± 283.57 to 97.96 ± 39.25, respectively, at post-intervention (TF3), demonstrating a statistically significant difference (p < 0.001). A higher percentage of participants in the SG achieved normal menstrual blood loss compared to the TG (93.5% vs 74.2%). The SG showed a considerable improvement in total SF-36 scores (73.56%) compared to the TG (65.65%), with a statistically significant difference (p < 0.001). Additionally, no serious adverse events were reported in either group. Notably, machine learning algorithms, particularly AB and KNN, demonstrated the highest accuracy within cross-validation models for both primary and secondary outcomes. Conclusion: The A. arabica and C. camphora vaginal suppository is effective, cost-effective, and safe in controlling HMB. This botanical vaginal suppository provides a novel and innovative alternative to traditional interventions, demonstrating promise as an effective management approach for HMB.

20.
PLoS One ; 18(4): e0284522, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37079536

RESUMO

Microbe organisms make up approximately 60% of the earth's living matter and the human body is home to millions of microbe organisms. Microbes are microbial threats to health and may lead to several diseases in humans like toxoplasmosis and malaria. The microbiological toxoplasmosis disease in humans is widespread, with a seroprevalence of 3.6-84% in sub-Saharan Africa. This necessitates an automated approach for microbe organisms detection. The primary objective of this study is to predict microbe organisms in the human body. A novel hybrid microbes classifier (HMC) is proposed in this study which is based on a decision tree classifier and extra tree classifier using voting criteria. Experiments involve different machine learning and deep learning models for detecting ten different living microforms of life. Results suggest that the proposed HMC approach achieves a 98% accuracy score, 98% geometric mean score, 97% precision score, and 97% Cohen Kappa score. The proposed model outperforms employed models, as well as, existing state-of-the-art models. Moreover, the k-fold cross-validation corroborates the results as well. The research helps microbiologists identify the type of microbe organisms with high accuracy and prevents many diseases through early detection.


Assuntos
Algoritmos , Aprendizado de Máquina , Humanos , Estudos Soroepidemiológicos
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