Detalhe da pesquisa
1.
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
J Biol Chem
; 293(32): 12415-12428, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925593
2.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
J Biol Chem
; 291(16): 8486-99, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884336
3.
A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.
Mol Ther
; 23(1): 24-31, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189740
4.
New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.
J Biol Chem
; 289(46): 31777-31791, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288799
5.
SLPI and trappin-2 as therapeutic agents to target airway serine proteases in inflammatory lung diseases: current and future directions.
Biochem Soc Trans
; 39(5): 1441-6, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21936830
6.
The antibacterial and antifungal properties of trappin-2 (pre-elafin) do not depend on its protease inhibitory function.
FEBS J
; 275(9): 2008-20, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18341586
7.
Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family.
Biochimie
; 90(2): 284-95, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17964057
8.
Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.
J Med Chem
; 61(5): 1858-1870, 2018 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29442501
9.
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.
Biochem Pharmacol
; 131: 52-67, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193451
10.
Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.
FEBS J
; 283(3): 498-509, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607765
11.
Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).
Semin Immunopathol
; 35(4): 411-21, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385856
12.
Protection of lung epithelial cells from protease-mediated injury by trappin-2 A62L, an engineered inhibitor of neutrophil serine proteases.
Biochem Pharmacol
; 83(12): 1663-73, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22465040
13.
Secretory leukocyte protease inhibitor (SLPI) is, like its homologue trappin-2 (pre-elafin), a transglutaminase substrate.
PLoS One
; 6(6): e20976, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21687692
14.
Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases.
Protein Sci
; 18(3): 579-94, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19241385
15.
Proteolytic susceptibility of the serine protease inhibitor trappin-2 (pre-elafin): evidence for tryptase-mediated generation of elafin.
Biol Chem
; 386(4): 391-9, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15899702
16.
Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase.
Biochemistry
; 44(47): 15610-8, 2005 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16300411
17.
Fluorescence and FTIR study of pressure-induced structural modifications of horse liver alcohol dehydrogenase (HLADH).
Eur J Biochem
; 270(1): 119-28, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12492482