Detalhe da pesquisa
1.
CRISPR-Cas9n-mediated ELANE promoter editing for gene therapy of severe congenital neutropenia.
Mol Ther
; 2024 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38556793
2.
Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations.
Haematologica
; 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37855057
3.
CRISPR/Cas9-mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients.
Haematologica
; 105(3): 598-609, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31248972
4.
Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs.
STAR Protoc
; 3(2): 101400, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35600931
5.
NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells.
Stem Cell Res Ther
; 12(1): 112, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33546767
6.
The chemokine CXCL14 mediates platelet function and migration via direct interaction with CXCR4.
Cardiovasc Res
; 117(3): 903-917, 2021 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32239134
7.
iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia.
Cell Stem Cell
; 28(5): 906-922.e6, 2021 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33894142
8.
CRISPR/Cas9 Genome Editing of Human-Induced Pluripotent Stem Cells Followed by Granulocytic Differentiation.
Methods Mol Biol
; 2115: 471-483, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32006418
9.
Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Blood Adv
; 3(1): 63-71, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622144
10.
Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34+ cells preceding leukemic transformation.
Exp Hematol
; 71: 51-60, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30615903
11.
Correction: NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells.
Stem Cell Res Ther
; 14(1): 299, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858174
12.
iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia.
Cell Stem Cell
; 30(9): 1282, 2023 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37683606
13.
Simultaneous quantification of DNA damage and mitochondrial copy number by long-run DNA-damage quantification (LORD-Q).
Oncotarget
; 8(68): 112417-112425, 2017 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29348835
14.
Corrigendum to 'Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34+ cells preceding leukemic transformation' <[Experimental Hematology, Volume 71, 2019;71:51-60]>.
Exp Hematol
; 114: 61, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35952718
15.
Genome surveillance in pluripotent stem cells: Low apoptosis threshold and efficient antioxidant defense.
Mol Cell Oncol
; 3(2): e1052183, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27308586
16.
Novel AKT phosphorylation sites identified in the pluripotency factors OCT4, SOX2 and KLF4.
Cell Cycle
; 14(23): 3748-54, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26654770
17.
High glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cells.
Stem Cell Reports
; 4(5): 886-98, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937369
18.
Assessment of UV-C-induced water disinfection by differential PCR-based quantification of bacterial DNA damage.
J Microbiol Methods
; 149: 89-95, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29608927