Detalhe da pesquisa
1.
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
N Engl J Med
; 377(3): 211-221, 2017 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28538136
2.
Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux.
J Lipid Res
; 57(3): 398-409, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26658238
3.
Measurement of LDL-C after treatment with the CETP inhibitor anacetrapib.
J Lipid Res
; 54(2): 467-72, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23172660
4.
Safety of anacetrapib in patients with or at high risk for coronary heart disease.
N Engl J Med
; 363(25): 2406-15, 2010 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21082868
5.
Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib.
J Lipid Res
; 53(3): 540-547, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22180633
6.
Efficacy and safety after cessation of treatment with the cholesteryl ester transfer protein inhibitor anacetrapib (MK-0859) in patients with primary hypercholesterolemia or mixed hyperlipidemia.
Am Heart J
; 162(4): 708-16, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21982664
7.
Novel strategy using F1-congenic mice for validation of QTLs: studies at the proximal chromosome 10 atherosclerosis susceptibility locus.
Arterioscler Thromb Vasc Biol
; 29(5): 678-83, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251590
8.
Design of the DEFINE trial: determining the EFficacy and tolerability of CETP INhibition with AnacEtrapib.
Am Heart J
; 158(4): 513-519.e3, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19781408
9.
Increased neointimal formation after surgical vein grafting in a murine model of type 2 diabetes.
Circulation
; 114(1 Suppl): I302-7, 2006 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16820590
10.
Diabetes induces endothelial dysfunction but does not increase neointimal formation in high-fat diet fed C57BL/6J mice.
Circ Res
; 96(11): 1178-84, 2005 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15879311
11.
Diabetic vascular disease: an experimental objective.
Arterioscler Thromb Vasc Biol
; 26(8): 1693-701, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16763160
12.
A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse.
Genetics
; 160(4): 1599-608, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11973313
13.
Differential effects of angiotensin II on atherogenesis at the aortic sinus and descending aorta of apolipoprotein-E-deficient mice.
Am J Hypertens
; 18(4 Pt 1): 486-92, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831357
14.
Neointimal formation after endovascular arterial injury is markedly attenuated in db/db mice.
Arterioscler Thromb Vasc Biol
; 23(11): 2027-33, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14500292
15.
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.
Arterioscler Thromb Vasc Biol
; 23(1): 117-22, 2003 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12524234
16.
High-density lipoproteins retard the progression of atherosclerosis and favorably remodel lesions without suppressing indices of inflammation or oxidation.
Arterioscler Thromb Vasc Biol
; 24(10): 1904-9, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15319266
17.
Changes in LDL particle concentrations after treatment with the cholesteryl ester transfer protein inhibitor anacetrapib alone or in combination with atorvastatin.
J Clin Lipidol
; 9(1): 93-102, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670366
18.
Evaluation of lipids, drug concentration, and safety parameters following cessation of treatment with the cholesteryl ester transfer protein inhibitor anacetrapib in patients with or at high risk for coronary heart disease.
Am J Cardiol
; 113(1): 76-83, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24188894
19.
Lipids, safety parameters, and drug concentrations after an additional 2 years of treatment with anacetrapib in the DEFINE study.
J Cardiovasc Pharmacol Ther
; 19(6): 543-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24737712
20.
Effects of anacetrapib on plasma lipids, apolipoproteins and PCSK9 in healthy, lean rhesus macaques.
Eur J Pharmacol
; 740: 410-6, 2014 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24769414