Detalhe da pesquisa
1.
Phosphorylation of ARHGAP19 by CDK1 and ROCK regulates its subcellular localization and function during mitosis.
J Cell Sci
; 131(5)2018 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420299
2.
Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response.
Blood
; 130(6): 732-741, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28588019
3.
The RhoGAP ARHGAP19 controls cytokinesis and chromosome segregation in T lymphocytes.
J Cell Sci
; 127(Pt 2): 400-10, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24259668
4.
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
J Inherit Metab Dis
; 39(6): 807-820, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27469509
5.
Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs.
Mol Cell Biol
; 27(6): 2324-42, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17210633
6.
Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib.
Nat Med
; 24(8): 1167-1177, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30013198
7.
Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.
ACS Med Chem Lett
; 9(4): 300-305, 2018 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29670690
8.
Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen.
Mol Cell Biol
; 24(14): 6311-23, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15226433
9.
Identification of mechanisms underlying transporter associated with antigen processing deficiency in metastatic murine carcinomas.
Cancer Res
; 65(16): 7485-92, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16103103
10.
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov
; 7(5): 478-493, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193778
11.
Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1022: 290-297, 2016 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27131892
12.
Functional characterization of IL-13 receptor alpha2 gene promoter: a critical role of the transcription factor STAT6 for regulated expression.
Oncogene
; 22(22): 3386-94, 2003 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12776189
13.
Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors.
Cancer Res
; 68(23): 9601-7, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19047136
14.
Epigenetic control of the immune escape mechanisms in malignant carcinomas.
Mol Cell Biol
; 27(22): 7886-94, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17875943
15.
Absence of caprin-1 results in defects in cellular proliferation.
J Immunol
; 175(7): 4274-82, 2005 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16177067
16.
Pure lipopolysaccharide or synthetic lipid A induces activation of p21Ras in primary macrophages through a pathway dependent on Src family kinases and PI3K.
J Immunol
; 175(12): 8236-41, 2005 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16339563