Detalhe da pesquisa
1.
"Quasi nonparametric" upper tolerance limits for occupational exposure evaluations.
J Occup Environ Hyg
; 12(5): 342-9, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25647534
2.
Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging.
Bioconjug Chem
; 25(12): 2123-8, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25418333
3.
Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers.
J Med Chem
; 67(8): 6064-6080, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38595098
4.
Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry.
Bioconjug Chem
; 24(6): 1057-67, 2013 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23688208
5.
Optimizing the Therapeutic Window of Targeted Drugs in Oncology: Potency-Guided First-in-Human Studies.
Clin Transl Sci
; 14(2): 536-543, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33048459
6.
Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity.
Toxicol Pathol
; 38(5): 691-702, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20616376
7.
Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides.
Drug Metab Dispos
; 37(12): 2375-82, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19741038
8.
Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.
Drug Metab Dispos
; 36(12): 2492-8, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18755851
9.
Pharmacokinetics and brain penetration of casopitant, a potent and selective neurokinin-1 receptor antagonist, in the ferret.
Drug Metab Dispos
; 36(9): 1846-52, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18556439
10.
Impact of erythrocyte Duffy antigen genetic polymorphism on the distribution of GroBeta-T, a novel human CXC chemokine.
J Pharm Pharm Sci
; 10(4): 486-95, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18396564
11.
Demand forecasting and capacity management in primary care.
Physician Exec
; 38(1): 30-4, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23885507
12.
Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor.
J Pharm Sci
; 95(12): 2657-72, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16892205
13.
Pharmacokinetic and pharmacodynamic modeling of humanized anti-factor IX antibody (SB 249417) in humans.
Clin Pharmacol Ther
; 71(4): 235-45, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11956506
14.
Rational Design, Synthesis, and SAR of a Novel Thiazolopyrimidinone Series of Selective PI3K-beta Inhibitors.
ACS Med Chem Lett
; 3(7): 524-9, 2012 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900504
15.
Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials.
J Pharm Sci
; 98(1): 362-77, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18563832
16.
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
J Med Chem
; 52(5): 1408-15, 2009 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222165
17.
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
J Med Chem
; 52(7): 1828-44, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19284751
18.
CD4 coating, but not CD4 depletion, is a predictor of efficacy with primatized monoclonal anti-CD4 treatment of active rheumatoid arthritis.
J Rheumatol
; 29(2): 220-9, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11838838