Detalhe da pesquisa
1.
Impaired insulin signalling and allostatic load in Alzheimer disease.
Nat Rev Neurosci
; 23(4): 215-230, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228741
2.
Leptin receptor reactivation restores brain function in early-life Lepr-deficient mice.
Brain
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38650574
3.
AAV-mediated neuronal expression of an scFv antibody selective for Aß oligomers protects synapses and rescues memory in Alzheimer models.
Mol Ther
; 31(2): 409-419, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36369741
4.
Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia.
Alzheimers Dement
; 19(6): 2595-2604, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36465055
5.
Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice.
Alzheimers Dement
; 19(12): 5418-5436, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37204850
6.
Lung inflammation induced by silica particles triggers hippocampal inflammation, synapse damage and memory impairment in mice.
J Neuroinflammation
; 19(1): 303, 2022 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36527099
7.
Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice.
J Pathol
; 254(3): 244-253, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33797777
8.
Interleukin-1ß mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-ß oligomers.
J Neuroinflammation
; 18(1): 54, 2021 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33612100
9.
Dementia in Latin America: Paving the way toward a regional action plan.
Alzheimers Dement
; 17(2): 295-313, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33634602
10.
Protective actions of exercise-related FNDC5/Irisin in memory and Alzheimer's disease.
J Neurochem
; 155(6): 602-611, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32396989
11.
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-ß oligomers.
J Biol Chem
; 293(6): 1957-1975, 2018 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284679
12.
Tau ablation in mice leads to pancreatic ß cell dysfunction and glucose intolerance.
FASEB J
; 32(6): 3166-3173, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401605
13.
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease.
J Pathol
; 245(1): 85-100, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29435980
14.
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aß Oligomers in Alzheimer's Disease Model.
J Neurosci
; 37(28): 6797-6809, 2017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607171
15.
Amyloid-ß oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons.
J Biol Chem
; 292(18): 7395-7406, 2017 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28302722
16.
Interaction of amyloid-ß (Aß) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice.
J Biol Chem
; 292(18): 7327-7337, 2017 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283575
17.
Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-ß Oligomers in Mice.
J Neurosci
; 36(48): 12106-12116, 2016 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27903721
18.
Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-ß oligomers in mice.
Brain Behav Immun
; 64: 140-151, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28412140
19.
Alzheimer's disease-like pathology induced by amyloid-ß oligomers in nonhuman primates.
J Neurosci
; 34(41): 13629-43, 2014 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25297091
20.
Memantine rescues transient cognitive impairment caused by high-molecular-weight aß oligomers but not the persistent impairment induced by low-molecular-weight oligomers.
J Neurosci
; 33(23): 9626-34, 2013 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23739959