Detalhe da pesquisa
1.
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells.
Cancer Immunol Immunother
; 73(1): 11, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38231448
2.
Identification of novel human CC chemokine receptor 8 (CCR8) antagonists via the synthesis of naphthalene amide and sulfonamide isosteres.
Bioorg Chem
; 145: 107181, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38354503
3.
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3-b]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase.
Molecules
; 29(5)2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474466
4.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
5.
Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents.
Bioorg Med Chem Lett
; 95: 129490, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770001
6.
Synthesis and structure-activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists.
Bioorg Chem
; 139: 106755, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37544272
7.
Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model.
Cell Mol Life Sci
; 79(6): 293, 2022 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35562519
8.
Exploration of Pyrido[3,4-d]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2.
Molecules
; 28(5)2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36903345
9.
Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities.
Molecules
; 28(23)2023 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38067641
10.
Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis.
Molecules
; 28(7)2023 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37049986
11.
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses.
J Am Chem Soc
; 144(7): 2905-2920, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35142215
12.
Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures.
J Med Virol
; 94(7): 3101-3111, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35229317
13.
Discovery of ( ±)-3-(1H-pyrazol-1-yl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity.
Mol Divers
; 26(3): 1357-1371, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165689
14.
Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives.
J Mol Struct
; : 134135, 2022 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36101881
15.
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors.
Molecules
; 28(1)2022 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615354
16.
Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication.
Molecules
; 27(3)2022 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164317
17.
Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.
J Infect Dis
; 224(5): 749-753, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244768
18.
In vitro activity of itraconazole against SARS-CoV-2.
J Med Virol
; 93(7): 4454-4460, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33666253
19.
Palladium-catalyzed cross-coupling reactions on a bromo-naphthalene scaffold in the search for novel human CC chemokine receptor 8 (CCR8) antagonists.
Bioorg Chem
; 107: 104560, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33383325
20.
Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists.
Molecules
; 26(20)2021 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684878