Detalhe da pesquisa
1.
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription.
Genes Dev
; 34(21-22): 1452-1473, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33060135
2.
Electrolytic macrocyclizations: scalable synthesis of a diazonamide-based drug development candidate.
Angew Chem Int Ed Engl
; 54(16): 4818-22, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25729008
3.
Thermal Nickel-Catalyzed N-Arylation of NH-Sulfoximines with (Hetero)aryl Chlorides Enabled by PhPAd-DalPhos Ligation.
Org Lett
; 26(7): 1326-1331, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329789
4.
Nucleotide competing reverse transcriptase inhibitors: discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors.
Bioorg Med Chem Lett
; 23(9): 2781-6, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23545107
5.
Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: in vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors.
Bioorg Med Chem Lett
; 23(13): 3967-75, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23673016
6.
Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors.
Bioorg Med Chem Lett
; 23(9): 2775-80, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23511023
7.
Inhibition of HIV-1 capsid assembly: optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold.
Bioorg Med Chem Lett
; 22(24): 7512-7, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23122820
8.
Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly.
Bioorg Med Chem Lett
; 21(1): 398-404, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21087861
9.
Chemical synthesis of 2beta-amino-5alpha-androstane-3alpha,17beta-diol N-derivatives and their antiproliferative effect on HL-60 human leukemia cells.
Bioorg Med Chem
; 16(9): 5062-77, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18375126
10.
Efficient nucleophilic aromatic substitution between aryl nitrofluorides and alkynes.
Org Lett
; 9(14): 2741-3, 2007 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17552534
11.
Total synthesis of (+)-cystothiazole A.
Org Lett
; 5(22): 4163-5, 2003 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-14572275
12.
2beta-(N-substituted piperazino)-5alpha-androstane-3alpha,17beta-diols: parallel solid-phase synthesis and antiproliferative activity on human leukemia HL-60 cells.
J Comb Chem
; 9(3): 347-58, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17441773
13.
Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases.
Bioorg Med Chem Lett
; 17(16): 4437-41, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17583503
14.
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency.
Bioorg Med Chem Lett
; 14(4): 967-71, 2004 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15013003