Detalhe da pesquisa
1.
Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions.
Proc Natl Acad Sci U S A
; 121(8): e2314914121, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38346202
2.
The Super-Relaxed State and Length Dependent Activation in Porcine Myocardium.
Circ Res
; 129(6): 617-630, 2021 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34365814
3.
Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients.
Sci Adv
; 9(30): eabo7622, 2023 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506209
4.
Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors.
bioRxiv
; 2023 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37090664
5.
The Impact of Mavacamten on the Pathophysiology of Hypertrophic Cardiomyopathy: A Narrative Review.
Am J Cardiovasc Drugs
; 22(5): 497-510, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35435607
6.
Acute Effects of Pimobendan on Cardiac Function in Dogs With Tachycardia Induced Dilated Cardiomyopathy: A Randomized, Placebo-Controlled, Crossover Study.
Front Vet Sci
; 8: 646437, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34277749
7.
Direct Interstitial Decongestion in an Animal Model of Acute-on-Chronic Ischemic Heart Failure.
JACC Basic Transl Sci
; 6(11): 872-881, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34869951
8.
Effects of perzinfotel on the minimum alveolar concentration of isoflurane in dogs when administered as a preanesthetic via various routes or in combination with butorphanol.
Am J Vet Res
; 71(6): 604-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20513173
9.
Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial.
Eur J Heart Fail
; 22(9): 1649-1658, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558989
10.
Electrotonic remodeling following myocardial infarction in dogs susceptible and resistant to sudden cardiac death.
J Appl Physiol (1985)
; 104(2): 386-93, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18048585
11.
Intravenous Infusion of the Novel HNO Donor BMS-986231 Is Associated With Beneficial Inotropic, Lusitropic, and Vasodilatory Properties in 2 Canine Models of Heart Failure.
JACC Basic Transl Sci
; 3(5): 625-638, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30456334
12.
CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction-A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat.
Front Physiol
; 8: 894, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29209225
13.
Vacuum-assisted apical suction devices induce passive electrical changes consistent with myocardial ischemia during off-pump coronary artery bypass graft surgery.
Eur J Cardiothorac Surg
; 30(6): 873-6, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049869
14.
Early time course of myocardial electrical impedance during acute coronary artery occlusion in pigs, dogs, and humans.
J Appl Physiol (1985)
; 99(4): 1576-81, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15961608
15.
Myocardial electrotonic response to submaximal exercise in dogs with healed myocardial infarctions: evidence for ß-adrenoceptor mediated enhanced coupling during exercise testing.
Front Physiol
; 6: 25, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25698976
16.
Dose-Dependent Hemodynamic, Biochemical, and Tissue Oxygen Effects of OC99 following Severe Oxygen Debt Produced by Hemorrhagic Shock in Dogs.
Crit Care Res Pract
; 2014: 864237, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25405028
17.
Cardiac function after acute support with direct mechanical ventricular actuation in chronic heart failure.
ASAIO J
; 60(6): 701-6, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25238499
18.
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia.
J Cardiovasc Pharmacol Ther
; 19(1): 121-32, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24288396
19.
Evaluation of oscillometric and vascular access port arterial blood pressure measurement techniques versus implanted telemetry in anesthetized cats.
Am J Vet Res
; 72(8): 1015-21, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21801057
20.
Editorial: Cardiac electronic remodeling and susceptibility to arrhythmias: an introduction and brief historical overview.
Front Physiol
; 6: 196, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26217235