Detalhe da pesquisa
1.
Antibody drug conjugates of cleavable amino-benzoyl-maytansinoids.
Bioorg Med Chem
; 28(23): 115785, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33099182
2.
Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids.
Bioorg Med Chem
; 26(9): 2271-2279, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29605304
3.
A Bispecific METxMET Antibody-Drug Conjugate with Cleavable Linker Is Processed in Recycling and Late Endosomes.
Mol Cancer Ther
; 22(3): 357-370, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36861363
4.
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Neurobiol Pain
; 14: 100136, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099276
5.
Allogeneic CD20-targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B-cell lymphoma models.
Clin Transl Immunology
; 11(2): e1373, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35136603
6.
Development of Novel Glucocorticoids for Use in Antibody-Drug Conjugates for the Treatment of Inflammatory Diseases.
J Med Chem
; 64(16): 11958-11971, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378927
7.
A BCMAxCD3 bispecific T cell-engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells.
Blood Adv
; 5(5): 1291-1304, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33651100
8.
A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade.
Mol Cancer Ther
; 20(10): 1966-1976, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34315762
9.
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning.
Sci Rep
; 11(1): 14397, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34257348
10.
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models.
Clin Cancer Res
; 26(6): 1408-1419, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848185
11.
A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.
Sci Transl Med
; 11(497)2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217340
12.
The human c-Fes tyrosine kinase binds tubulin and microtubules through separate domains and promotes microtubule assembly.
Mol Cell Biol
; 24(21): 9351-8, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15485904
13.
The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase.
Biochem J
; 399(1): 141-50, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16792528
14.
Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs.
Mol Cancer Ther
; 16(4): 681-693, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28108597
15.
Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers.
Mol Cancer Ther
; 16(7): 1299-1311, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377489
16.
NF-kappaB and TNF-alpha stimulate androgen receptor expression in Sertoli cells.
Mol Cell Endocrinol
; 201(1-2): 1-12, 2003 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12706288
17.
ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models.
Mol Cancer Ther
; 13(5): 1345-55, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24634416
18.
A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer.
J Biol Chem
; 281(13): 8829-35, 2006 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-16455651
19.
Regulation of c-Fes tyrosine kinase activity by coiled-coil and SH2 domains: analysis with Saccharomyces cerevisiae.
Biochemistry
; 42(12): 3567-74, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12653561