Detalhe da pesquisa
1.
Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments.
J Am Chem Soc
; 142(10): 4904-4915, 2020 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32058716
2.
Exploring Binding Mechanisms in Nuclear Hormone Receptors by Monte Carlo and X-ray-derived Motions.
Biophys J
; 112(6): 1147-1156, 2017 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28355542
3.
Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists.
J Med Chem
; 65(19): 12956-12969, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167503
4.
Discovery of novel class 1 phosphatidylinositide 3-kinases (PI3K) fragment inhibitors through structure-based virtual screening.
Bioorg Med Chem Lett
; 21(2): 829-35, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21169017
5.
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.
J Med Chem
; 64(14): 9906-9915, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34197114
6.
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach.
Stem Cells Transl Med
; 9(1): 47-60, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31508905
7.
Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease.
J Med Chem
; 62(9): 4312-4324, 2019 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30869888
8.
Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
J Med Chem
; 61(8): 3674-3684, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29605997
9.
Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.
ChemMedChem
; 12(1): 50-65, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27897427
10.
RAR-related orphan receptor A isoform 1 (RORa1) is disrupted by a balanced translocation t(4;15)(q22.3;q21.3) associated with severe obesity.
Eur J Hum Genet
; 13(8): 928-34, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15886715