Detalhe da pesquisa
1.
Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a.
Nucleic Acids Res
; 52(9): 5241-5256, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38647045
2.
Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation.
Mol Cell
; 63(5): 852-64, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27546790
3.
Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter.
Nucleic Acids Res
; 50(13): 7511-7528, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819191
4.
Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases.
Nucleic Acids Res
; 48(10): 5591-5602, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32286652
5.
What is all this fuss about Tus? Comparison of recent findings from biophysical and biochemical experiments.
Crit Rev Biochem Mol Biol
; 53(1): 49-63, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29108427
6.
Why Argonaute is needed to make microRNA target search fast and reliable.
Semin Cell Dev Biol
; 65: 20-28, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27235676
7.
Crowding-induced transcriptional bursts dictate polymerase and nucleosome density profiles along genes.
Nucleic Acids Res
; 45(13): 7623-7632, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28586463
8.
Switching between Exonucleolysis and Replication by T7 DNA Polymerase Ensures High Fidelity.
Biophys J
; 112(4): 575-583, 2017 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28256218
9.
Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.
Nat Chem Biol
; 11(8): 579-85, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26147356
10.
Backtracking behavior in viral RNA-dependent RNA polymerase provides the basis for a second initiation site.
Nucleic Acids Res
; 43(21): 10421-9, 2015 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26496948
11.
Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution.
Proc Natl Acad Sci U S A
; 111(42): 15090-5, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288749
12.
Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows.
Nature
; 467(7315): 617-21, 2010 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20852613
13.
Active multistage coarsening of actin networks driven by myosin motors.
Proc Natl Acad Sci U S A
; 108(23): 9408-13, 2011 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593409
14.
Stress-enhanced gelation: a dynamic nonlinearity of elasticity.
Phys Rev Lett
; 110(1): 018103, 2013 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383843
15.
High-throughput single-molecule experiments reveal heterogeneity, state switching, and three interconnected pause states in transcription.
Cell Rep
; 39(4): 110749, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476989
16.
A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity.
Nat Commun
; 13(1): 1367, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35292641
17.
Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity.
Nat Commun
; 13(1): 474, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35078987
18.
The nucleotide addition cycle of the SARS-CoV-2 polymerase.
Cell Rep
; 36(9): 109650, 2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433083
19.
The nucleotide addition cycle of the SARS-CoV-2 polymerase.
bioRxiv
; 2021 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33791706
20.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
bioRxiv
; 2021 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851161