Detalhe da pesquisa
1.
Inositol polyphosphate-protein interactions: Implications for microbial pathogenicity.
Cell Microbiol
; 23(6): e13325, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33721399
2.
Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes.
Mol Cell Proteomics
; 17(12): 2462-2479, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206180
3.
The Early Innate Immune Response to, and Phagocyte-Dependent Entry of, Cryptococcus neoformans Map to the Perivascular Space of Cortical Post-Capillary Venules in Neurocryptococcosis.
Am J Pathol
; 188(7): 1653-1665, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29929915
4.
Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans.
Biochim Biophys Acta Biomembr
; 1859(11): 2224-2233, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28865794
5.
Arg1 from Cryptococcus neoformans lacks PI3 kinase activity and conveys virulence roles via its IP3-4 kinase activity.
mBio
; : e0060824, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38742909
6.
Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase.
Infect Immun
; 81(4): 1245-55, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23381992
7.
Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans.
mBio
; 14(2): e0355122, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37017534
8.
TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans.
Biomolecules
; 12(10)2022 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36291735
9.
Miltefosine induces apoptosis-like cell death in yeast via Cox9p in cytochrome c oxidase.
Mol Pharmacol
; 80(3): 476-85, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21610197
10.
Monitoring Glycolysis and Respiration Highlights Metabolic Inflexibility of Cryptococcus neoformans.
Pathogens
; 9(9)2020 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32839374
11.
IP7-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery.
mBio
; 11(5)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33082258
12.
Calcium Binding Protein Ncs1 Is Calcineurin Regulated in Cryptococcus neoformans and Essential for Cell Division and Virulence.
mSphere
; 5(5)2020 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907953
13.
Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities.
Front Cell Infect Microbiol
; 9: 248, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31380293
14.
The PHO signaling pathway directs lipid remodeling in Cryptococcus neoformans via DGTS synthase to recycle phosphate during phosphate deficiency.
PLoS One
; 14(2): e0212651, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30789965
15.
IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote Cryptococcus neoformans infection in a mouse model.
Virulence
; 8(8): 1833-1848, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976803
16.
Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH.
mSphere
; 2(1)2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28144629
17.
Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery.
J Fungi (Basel)
; 2(3)2016 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29376941
18.
Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence.
Sci Rep
; 6: 23927, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27033523
19.
Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity.
mBio
; 6(3): e00531-15, 2015 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26037119
20.
Rapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory.
PLoS One
; 10(1): e0117186, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25625210