Detalhe da pesquisa
1.
Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi.
Bioorg Med Chem Lett
; 30(1): 126779, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31706667
2.
Synthesis and Anti-Trypanosoma cruzi Activity of 3-Cyanopyridine Derivatives.
ACS Omega
; 9(20): 22360-22370, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799347
3.
Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics.
Front Pharmacol
; 12: 774069, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35069198
4.
Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents.
RSC Med Chem
; 11(11): 1267-1274, 2020 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085041
5.
Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei.
Future Med Chem
; 11(13): 1537-1551, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31469332
6.
Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors.
Future Med Chem
; 9(7): 641-657, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28509592
7.
Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents.
J Med Chem
; 57(6): 2380-92, 2014 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24533839
8.
Analysis of cytokinin nucleotides by capillary zone electrophoresis with diode array and mass spectrometric detection in a recombinant enzyme in vitro reaction.
Anal Chim Acta
; 751: 176-81, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23084068
9.
(E)-4-Hydroxy-3-methylbut-2-enyl diphosphate: an intermediate in the formation of terpenoids in plant chromoplasts.
Angew Chem Int Ed Engl
; 41(14): 2604-7, 2002 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12203549
10.
A proposed mechanism for the reductive ring opening of the cyclodiphosphate MEcPP, a crucial transformation in the new DXP/MEP pathway to isoprenoids based on modeling studies and feeding experiments.
Chembiochem
; 5(3): 311-23, 2004 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14997523