Detalhe da pesquisa
1.
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function.
Nat Chem Biol
; 6(5): 359-68, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20383151
2.
Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway.
Cancer Cell
; 5(5): 501-12, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15144957
3.
IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.
Mol Cell Biol
; 22(6): 1754-66, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11865055
4.
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.
Mol Biol Cell
; 15(11): 5064-74, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15356269
5.
RNAi and HTS: exploring cancer by systematic loss-of-function.
Oncogene
; 23(51): 8392-400, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15517021
6.
Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin.
Oncogene
; 23(39): 6621-9, 2004 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15208666
7.
Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction.
Chem Biol
; 10(8): 759-67, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12954335
8.
Identification of a candidate therapeutic antibody for treatment of canine B-cell lymphoma.
Vet Immunol Immunopathol
; 164(3-4): 148-59, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25764941
9.
Activation and suppression of the TRAIL death-receptor pathway in chemotherapy sensitive and resistant follicular lymphoma cells.
Cancer Biol Ther
; 2(5): 534-40, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14614322
10.
A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function.
Proc Natl Acad Sci U S A
; 102(42): 15195-200, 2005 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16210249
11.
Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.
J Biol Chem
; 279(33): 35047-52, 2004 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-15173176
12.
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening.
Mol Cell
; 12(3): 627-37, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-14527409
13.
Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi.
Semin Cancer Biol
; 13(4): 293-300, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-14563124
14.
ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis.
J Biol Chem
; 277(34): 30454-62, 2002 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12048196