Detalhe da pesquisa
1.
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription.
Nucleic Acids Res
; 50(5): 2566-2586, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150567
2.
Fetal growth at term and placental oxidative stress in a tissue micro-array model: a histological and immunohistochemistry study.
Histochem Cell Biol
; 160(4): 293-306, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37306741
3.
Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells.
Nucleic Acids Res
; 48(2): 646-664, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754707
4.
The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.
PLoS Genet
; 13(4): e1006752, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28419090
5.
The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro.
J Cell Sci
; 128(21): 3961-76, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26403201
6.
Selective class IIa HDAC inhibitors: myth or reality.
Cell Mol Life Sci
; 72(1): 73-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189628
7.
Class IIa HDACs repressive activities on MEF2-depedent transcription are associated with poor prognosis of ER⺠breast tumors.
FASEB J
; 27(3): 942-54, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23159930
8.
Transcription of endogenous retroviruses in senescent cells contributes to the accumulation of double-stranded RNAs that trigger an anti-viral response that reinforces senescence.
Cell Death Dis
; 15(2): 157, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383514
9.
NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells.
Biochim Biophys Acta Mol Cell Res
; 1871(1): 119606, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37852325
10.
Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J Mol Biol
; 436(9): 168541, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38492719
11.
Changes in chromatin accessibility and transcriptional landscape induced by HDAC inhibitors in TP53 mutated patient-derived colon cancer organoids.
Biomed Pharmacother
; 173: 116374, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447451
12.
Super-enhancer landscape rewiring in cancer: The epigenetic control at distal sites.
Int Rev Cell Mol Biol
; 380: 97-148, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657861
13.
Dual-targeting peptides@PMO, a mimetic to the pro-apoptotic protein Smac/DIABLO for selective activation of apoptosis in cancer cells.
Front Pharmacol
; 14: 1237478, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37711175
14.
Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells.
iScience
; 26(12): 108566, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38144458
15.
Endogenous Retroviruses (ERVs): Does RLR (RIG-I-Like Receptors)-MAVS Pathway Directly Control Senescence and Aging as a Consequence of ERV De-Repression?
Front Immunol
; 13: 917998, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35757716
16.
Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy.
J Cachexia Sarcopenia Muscle
; 13(2): 1339-1359, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170869
17.
Photosensitization of pancreatic cancer cells by cationic alkyl-porphyrins in free form or engrafted into POPC liposomes: The relationship between delivery mode and mechanism of cell death.
J Photochem Photobiol B
; 231: 112449, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504235
18.
Quis Custodiet Ipsos Custodes (Who Controls the Controllers)? Two Decades of Studies on HDAC9.
Life (Basel)
; 11(2)2021 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513699
19.
HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.
Genome Biol
; 22(1): 129, 2021 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33966634
20.
Enhancing Proteotoxic Stress in Leiomyosarcoma Cells Triggers Mitochondrial Dysfunctions, Cell Death, and Antitumor Activity in vivo.
Mol Cancer Ther
; 20(6): 1039-1051, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785653