Assuntos
Vírus da Leucose Aviária , Leucose Aviária , Genitália Masculina/microbiologia , Testículo/microbiologia , Replicação Viral , Animais , Embrião de Galinha , Galinhas , Tecido Conjuntivo/microbiologia , Epididimo/microbiologia , Corpos de Inclusão Viral , Masculino , Microscopia Eletrônica , Músculo Liso/microbiologia , Células de Sertoli/citologia , Testículo/embriologia , Ducto Deferente/microbiologia , Ductos Mesonéfricos/microbiologiaAssuntos
Vírus da Leucose Aviária , Leucose Aviária/congênito , Animais , Encéfalo/microbiologia , Cartilagem/microbiologia , Embrião de Galinha , Testes de Fixação de Complemento , Tecido Conjuntivo/microbiologia , Epitélio/microbiologia , Gônadas/microbiologia , Intestinos/microbiologia , Rim/microbiologia , Fígado/microbiologia , Microscopia Eletrônica , Músculos/microbiologia , Oviductos/microbiologia , Baço/microbiologiaRESUMO
Chick embryo chorioallantoic membrane, infected with the Blacksburg strain of Newcastle disease virus, was examined with an electron microscope to investigate the sequence of viral-induced host cell alterations. These were evident mostly in the endodermal epithelial cells lining the allantoic sac and were divided arbitrarily into three stages. Stage 1 was characterized by commencement of cell hypertrophy and hyperplasia and presence of fewer cytoplasmic inclusion bodies normally found in the cells; in stage 2, juxtanuclear nucleocapsid-glycogen aggregates appeared, and there were increased numbers of microvilli; stage 3 was characterized by increased cytoplasmic density and evidence of viral assembly and release. The morphological features of viral assembly and the virion are also described.