Detalhe da pesquisa
1.
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy.
Cell
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38723627
2.
Circadian clocks guide dendritic cells into skin lymphatics.
Nat Immunol
; 22(11): 1375-1381, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663979
3.
Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks.
Genes Dev
; 35(5-6): 329-334, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602874
4.
The core clock transcription factor BMAL1 drives circadian ß-cell proliferation during compensatory regeneration of the endocrine pancreas.
Genes Dev
; 34(23-24): 1650-1665, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184223
5.
Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets.
PLoS Biol
; 20(8): e3001725, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921354
6.
Pancreatic α- and ß-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.
Genes Dev
; 31(4): 383-398, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275001
7.
SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
Cell
; 134(2): 317-28, 2008 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18662546
8.
In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
Proc Natl Acad Sci U S A
; 117(5): 2484-2495, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964806
9.
Circadian rhythm of lipid metabolism.
Biochem Soc Trans
; 50(3): 1191-1204, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35604112
10.
Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro.
Proc Natl Acad Sci U S A
; 114(41): E8565-E8574, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973848
11.
Proinflammatory Cytokines Perturb Mouse and Human Pancreatic Islet Circadian Rhythmicity and Induce Uncoordinated ß-Cell Clock Gene Expression via Nitric Oxide, Lysine Deacetylases, and Immunoproteasomal Activity.
Int J Mol Sci
; 22(1)2020 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33374803
12.
Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes.
Diabetologia
; 62(8): 1453-1462, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31134308
13.
Time zones of pancreatic islet metabolism.
Diabetes Obes Metab
; 20 Suppl 2: 116-126, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30230177
14.
MicroRNAs modulate core-clock gene expression in pancreatic islets during early postnatal life in rats.
Diabetologia
; 60(10): 2011-2020, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28674733
15.
The mammalian circadian timing system: organization and coordination of central and peripheral clocks.
Annu Rev Physiol
; 72: 517-49, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20148687
16.
Lysophosphatidylinositols Are Upregulated After Human ß-Cell Loss and Potentiate Insulin Release.
Diabetes
; 73(1): 93-107, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37862465
17.
Circadian gene expression is resilient to large fluctuations in overall transcription rates.
EMBO J
; 28(2): 123-34, 2009 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19078963
18.
Lipid metabolism around the body clocks.
Prog Lipid Res
; 91: 101235, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37187314
19.
Circadian organization of lipid landscape is perturbed in type 2 diabetic patients.
Cell Rep Med
; 4(12): 101299, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38016481
20.
Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis.
Nat Cell Biol
; 25(7): 975-988, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37414850