Detalhe da pesquisa
1.
Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
EMBO J
; 40(19): e107985, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34302370
2.
MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
Mol Cell
; 61(1): 68-83, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26748827
3.
Evaluation of N4-hydroxycytidine incorporation into nucleic acids of SARS-CoV-2-infected host cells by direct measurement with liquid chromatography-mass spectrometry.
Nucleosides Nucleotides Nucleic Acids
; : 1-9, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38741480
4.
Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design.
Nat Commun
; 15(1): 411, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195625
5.
Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res
; 221: 105778, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065245
6.
CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan.
Cell Cycle
; 22(13): 1563-1582, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37266562
7.
N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody.
iScience
; 26(10): 107786, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37731621
8.
MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression.
Cell Rep
; 39(9): 110879, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35649362
9.
Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication.
iScience
; 25(5): 104293, 2022 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35492218
10.
The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models.
Virus Res
; 302: 198469, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34090962
11.
The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis.
J Clin Invest
; 130(11): 5765-5781, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32701505
12.
CDK4 inhibition diminishes p53 activation by MDM2 antagonists.
Cell Death Dis
; 9(9): 918, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206211
13.
Expression, purification and crystallization of the ammonium transporter Amt-1 from Archaeoglobus fulgidus.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 61(Pt 9): 861-3, 2005 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16511180
14.
p63 antagonizes Wnt-induced transcription.
Cell Cycle
; 9(3): 580-87, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20107313
15.
Crystal structure of the archaeal ammonium transporter Amt-1 from Archaeoglobus fulgidus.
Proc Natl Acad Sci U S A
; 102(42): 14994-9, 2005 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16214888