Detalhe da pesquisa
1.
The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.
Nat Immunol
; 21(11): 1346-1358, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868929
2.
Health-related quality-of-life analysis from KEYNOTE-590: pembrolizumab plus chemotherapy versus chemotherapy for advanced esophageal cancer.
Oncologist
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38815152
3.
KEYNOTE-434 part B: A phase 1 study evaluating the combination of epacadostat, pembrolizumab, and chemotherapy in Japanese patients with previously untreated advanced non-small-cell lung cancer.
Invest New Drugs
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530565
4.
Pimitespib for the treatment of advanced gastrointestinal stromal tumors and other tumors.
Future Oncol
; 20(9): 507-519, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050698
5.
LEAP-014: first-line lenvatinib + pembrolizumab + chemotherapy in advanced/metastatic esophageal squamous cell carcinoma.
Future Oncol
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38695479
6.
First-line pembrolizumab plus chemotherapy for advanced/metastatic esophageal cancer: 1-year extended follow-up in the Japanese subgroup of the phase 3 KEYNOTE-590 study.
Esophagus
; 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607538
7.
Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study.
Lancet Oncol
; 24(8): 925-935, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37541273
8.
Phase I study of the irreversible fibroblast growth factor receptor 1-4 inhibitor futibatinib in Japanese patients with advanced solid tumors.
Cancer Sci
; 114(2): 574-585, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35838190
9.
First-in-human study of E7130 (a tumor microenvironment-ameliorating microtubule inhibitor) in patients with advanced solid tumors: Primary results of the dose-escalation part.
Cancer
; 129(15): 2348-2359, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37080942
10.
Current status of and future prospects for the treatment of unresectable or metastatic gastrointestinal stromal tumours.
Gastric Cancer
; 26(3): 339-351, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36913072
11.
Body weight loss as a prognostic and predictive factor in previously treated patients with metastatic gastric cancer: post hoc analyses of the randomized phase III TAGS trial.
Gastric Cancer
; 26(4): 626-637, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37106214
12.
A phase 1 trial of xentuzumab, an IGF-neutralizing antibody, in Japanese patients with advanced solid tumors.
Cancer Sci
; 113(3): 1010-1017, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34870878
13.
Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study.
Lancet
; 398(10302): 759-771, 2021 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34454674
14.
Eftozanermin alfa (ABBV-621) monotherapy in patients with previously treated solid tumors: findings of a phase 1, first-in-human study.
Invest New Drugs
; 40(4): 762-772, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467243
15.
Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS).
Gastric Cancer
; 25(3): 586-597, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34997449
16.
Prospective analysis of the expression status of FGFR2 and HER2 in colorectal and gastric cancer populations: DS-Screen Study.
Int J Colorectal Dis
; 37(6): 1393-1402, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35585358
17.
Characteristics and clinical outcomes of patients with advanced gastric or gastroesophageal cancer treated in and out of randomized clinical trials of first-line immune checkpoint inhibitors.
Int J Clin Oncol
; 27(9): 1413-1420, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35713753
18.
Phase II study of BKM120 in patients with advanced esophageal squamous cell carcinoma (EPOC1303).
Esophagus
; 19(4): 702-710, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35904643
19.
Second-line pembrolizumab versus chemotherapy in Japanese patients with advanced esophageal cancer: subgroup analysis from KEYNOTE-181.
Esophagus
; 19(1): 137-145, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591237
20.
First-line pembrolizumab + chemotherapy in Japanese patients with advanced/metastatic esophageal cancer from KEYNOTE-590.
Esophagus
; 19(4): 683-692, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35668304