Detalhe da pesquisa
1.
Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Bioorg Med Chem Lett
; 27(11): 2634-2640, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416131
2.
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-ß-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
Bioorg Med Chem Lett
; 27(18): 4323-4330, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835346
3.
Is there any need for new, long-acting nucleos(t)ide analogues for the treatment of hepatitis B infection?
J Hepatol
; 74(5): 1011-1014, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33715896
4.
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Bioorg Med Chem Lett
; 26(18): 4536-4541, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27520942
5.
HBV replication inhibitors.
Antiviral Res
; 179: 104815, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32380149
6.
Current and future use of nucleo(s)tide prodrugs in the treatment of hepatitis C virus infection.
Antivir Chem Chemother
; 26: 2040206618756430, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463095
7.
Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4'-Ethynyl-2-fluoro-2'-deoxyadenosine).
J Med Chem
; 61(20): 9218-9228, 2018 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30265808
8.
Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase.
J Med Chem
; 50(9): 2213-24, 2007 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17373783
9.
Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.
J Med Chem
; 49(3): 955-70, 2006 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16451062
10.
Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
J Med Chem
; 59(5): 1891-8, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26804933
11.
Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
J Med Chem
; 54(1): 392-5, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21142105