Detalhe da pesquisa
1.
Injured adult neurons regress to an embryonic transcriptional growth state.
Nature
; 581(7806): 77-82, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32376949
2.
Selective retinal ganglion cell loss and optic neuropathy in a humanized mouse model of familial dysautonomia.
Hum Mol Genet
; 31(11): 1776-1787, 2022 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34908112
3.
Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration.
Neurobiol Dis
; 162: 105581, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871739
4.
ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.
Am J Hum Genet
; 104(4): 638-650, 2019 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905397
5.
Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis.
PLoS Genet
; 13(7): e1006846, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28715425
6.
Lactobacillus plantarum prevents and mitigates alcohol-induced disruption of colonic epithelial tight junctions, endotoxemia, and liver damage by an EGF receptor-dependent mechanism.
FASEB J
; : fj201800351R, 2018 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29912589
7.
Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia.
Hum Mol Genet
; 25(6): 1116-28, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769677
8.
Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice.
Biochim Biophys Acta
; 1860(4): 765-74, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721332
9.
Role of major and brain-specific Sgce isoforms in the pathogenesis of myoclonus-dystonia syndrome.
Neurobiol Dis
; 98: 52-65, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27890709
10.
Familial Dysautonomia: Mechanisms and Models.
Genet Mol Biol
; 39(4): 497-514, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27561110
11.
Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.
J Neurosci
; 34(28): 9455-72, 2014 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25009276
12.
ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice.
Alcohol Clin Exp Res
; 39(8): 1465-75, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26173414
13.
Cutting edge: Conditional MHC class II expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responses.
J Immunol
; 191(2): 545-50, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23772037
14.
Presenilins are essential for regulating neurotransmitter release.
Nature
; 460(7255): 632-6, 2009 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19641596
15.
IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia.
Hum Mol Genet
; 21(23): 5078-90, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922231
16.
Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.
bioRxiv
; 2023 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993570
17.
Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.
Hum Mol Genet
; 18(1): 142-50, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18838463
18.
The hormonal action of IGF1 in postnatal mouse growth.
Proc Natl Acad Sci U S A
; 105(49): 19378-83, 2008 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19033454
19.
ATP-citrate lyase promotes axonal transport across species.
Nat Commun
; 12(1): 5878, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34620845
20.
Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.
Cell Rep
; 30(3): 642-657.e6, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31968243