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AIM: Cardiopulmonary resuscitation (CPR) is an emergency procedure where interpersonal distance cannot be maintained. There are and will always be outbreaks of infection from airborne diseases. Our objective was to assess the potential risk of airborne virus transmission during CPR in open-air conditions. METHODS: We performed advanced high-fidelity three-dimensional modelling and simulations to predict airborne transmission during out-of-hospital hands-only CPR. The computational model considers complex fluid dynamics and heat transfer phenomena such as aerosol evaporation, breakup, coalescence, turbulence, and local interactions between the aerosol and the surrounding fluid. Furthermore, we incorporated the effects of the wind speed/direction, the air temperature and relative humidity on the transport of contaminated saliva particles emitted from a victim during a resuscitation process based on an Airborne Infection Risk (AIR) Index. RESULTS: The results reveal low-risk conditions that include wind direction and high relative humidity and temperature. High-risk situations include wind directed to the rescuer, low humidity and temperature. Combinations of other conditions have an intermediate AIR Index and risk for the rescue team. CONCLUSIONS: The fluid dynamics, simulation-based AIR Index provides a classification of the risk of contagion by victim's aerosol in the case of hands-only CPR considering environmental factors such as wind speed and direction, relative humidity and temperature. Therefore, we recommend that rescuers perform a quick assessment of their airborne infectious risk before starting CPR in the open air and positioning themselves to avoid wind directed to their faces.
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COVID-19/transmissão , Reanimação Cardiopulmonar/efeitos adversos , Modelos Biológicos , Parada Cardíaca Extra-Hospitalar/terapia , SARS-CoV-2/patogenicidade , Aerossóis/efeitos adversos , COVID-19/complicações , COVID-19/virologia , Reanimação Cardiopulmonar/normas , Simulação por Computador , Guias como Assunto , Humanos , Umidade , Hidrodinâmica , Parada Cardíaca Extra-Hospitalar/complicações , Equipamento de Proteção Individual/normas , Medição de Risco/métodos , Medição de Risco/estatística & dados numéricos , Temperatura , VentoRESUMO
The effects of surface irregularities and imperfections on the thermal resistance at a solid-liquid interface have been investigated using molecular dynamics. The molecular model comprises liquid argon confined between silver walls. The surface roughness was designed using fractal theory, introducing stochastic patterns of multiple scales that resemble realistic surface geometries. In agreement with most previous studies, we find that increasing the strength of the solid-liquid interactions monotonically reduces the thermal resistance across smooth interfaces. Yet, the behavior of the thermal resistance across rough surfaces is more complex. Following the initially anticipated decrease, the thermal resistance starts to increase once the strength of solid-liquid interaction increases past a threshold. We attribute the above behavior to two competing phenomena, namely, the area of the solid-liquid interface and the introduction of vibrational anharmonicities and localization of phonons resulting from the surface roughness. Finally, we demonstrate that, for the same fractal dimension and depth of surface roughness, different surfaces practically have the same thermal resistance, solid-liquid radial distribution function, and liquid density profiles. We conclude that the above fractal parameters are useful in deriving reduced models for properties related to the surface geometry.
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The variation of the liquid properties in the vicinity of a solid surface complicates the description of heat transfer along solid-liquid interfaces. Using Molecular Dynamics simulations, this investigation aims to understand how the material properties, particularly the strength of the solid-liquid interaction, affect the thermal conductivity of the liquid at the interface. The molecular model consists of liquid argon confined by two parallel, smooth, solid walls, separated by a distance of 6.58 σ. We find that the component of the thermal conductivity parallel to the surface increases with the affinity of the solid and liquid.
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Cruise ships are densely populated ecosystems where infectious diseases can spread rapidly. Hence, early detection of infected individuals and risk assessment (RA) of the disease transmissibility are critical. Recent studies have investigated the long-term assessment of transmission risk on cruise ships; however, short-term approaches are limited by data unavailability. To this end, this work proposes a novel short-term knowledge-based method for RA of disease transmission based on fuzzy rules. These rules are constructed using knowledge elicited from domain experts. In contrast to previous approaches, the proposed method considers data captured by several sensors and the ship information system, according to a recently proposed smart ship design. Evaluation with agent-based simulations confirms the effectiveness of the proposed method across various cases.
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COVID-19 , Lógica Fuzzy , Navios , COVID-19/transmissão , Humanos , Medição de Risco , SARS-CoV-2 , PandemiasRESUMO
The design of rigid vortex generators (RVG) influences the thermal performance of various technologies. We employed Discrete Adjoint-Based Optimization to show the optimal development of vortex generators. Under turbulent flow conditions, different bi-objective functions on the RVG design were examined. Specifically, we aimed at an optimal RVG shape that minimizes the pressure drop and maximizes the local heat transfer in a rectangular channel. We show that an optimal design of an RVG can be obtained using computational fluid dynamics in conjunction with the Pareto Front at a computational cost of the order ~[Formula: see text]. We obtained three essential vortex generator shapes based on the RVG morphing technique. Compared to the baseline geometry of a delta winglet pair DWP, the first morphed design reduced the pressure drop by [Formula: see text], however, at the expense of a [Formula: see text] reduction in the Nusselt number. The second vortex generator design enhanced the heat transfer by [Formula: see text], however, at the cost of a significant increase in pressure drop of about [Formula: see text]. The final morphed design achieved the highest thermal performance factor of 1.28, representing a heat transfer enhancement of [Formula: see text] with a moderate increase in pressure drop of about [Formula: see text] compared to DWP vortex generators. Furthermore, we investigated the effect of introducing different size holes on the mass reduction of vortex generators and their thermal performances. The mass of vortex generators can be reduced by [Formula: see text] and with an increase of [Formula: see text] in thermal performance factor concerning the DWP baseline. The findings of this study will lead to highly efficient lightweight heat exchangers.
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This study presents a computational fluid dynamics, susceptible-infected-recovered-based epidemic model that relates weather conditions to airborne virus transmission dynamics. The model considers the relationship between weather seasonality, airborne virus transmission, and pandemic outbreaks. We examine multiple scenarios of the COVID-19 fifth wave in London, United Kingdom, showing the potential peak and the period occurring. The study also shows the importance of fluid dynamics and computational modeling in developing more advanced epidemiological models in the future.
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According to WHO, by 2050, at least one person out of two will suffer from an allergy disorder resulting from the accelerating air pollution associated with toxic gas emissions and climate change. Airborne pollen, and associated allergies, are major public health topics during the pollination season, and their effects are further strengthened due to climate change. Therefore, assessing the airborne pollen allergy risk is essential for improving public health. This study presents a new computational fluid dynamics methodology for risk assessment of local airborne pollen transport in an urban environment. Specifically, we investigate the local airborne pollen transport from trees on a university campus in the north of France. We produce risk assessment maps for pollen allergy for five consecutive days during the pollination season. The proposed methodology could be extended to larger built-up areas for different weather conditions. The risk assessment maps may also be integrated with smart devices, thus leading to decision-aid tools to better guide and protect the public against airborne pollen allergy.
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Rinite Alérgica Sazonal , Humanos , Rinite Alérgica Sazonal/epidemiologia , Rinite Alérgica Sazonal/etiologia , França/epidemiologia , Universidades , Medição de RiscoRESUMO
This study investigates how airborne pollen pellets (or grains) can cause severe respiratory-related problems in humans. Given that pollen pellets can capture ribonucleic acid viruses, we show that airborne pollen grains could transport airborne virus particles such as the airborne coronavirus (CoV) disease (COVID-19) or others. We consider the environmental conditions featuring the highest pollen concentration season and conduct computational multiphysics, multiscale modeling and simulations. The investigation concerns a prototype problem comprising the transport of 104 airborne pollen grains dropped from a mature willow tree at a wind speed of ( U wind = 4 km / h ) . We show how pollen grains can increase the coronavirus (CoV) transmission rate in a group of people, including some infected persons. In the case of high pollen grains concentrations in the air or during pollination in the spring, the social distance of 2 m does not hold as a health safety measure for an outdoor crowd. Thus, the public authorities should revise the social distancing guidelines.
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It is well established that the data reported for the daily number of infected cases during the first wave of the COVID-19 pandemic were inaccurate, primarily due to insufficient tracing across the populations. Due to the uncertainty of the first wave data mixed with the second wave data, the general conclusions drawn could be misleading. We present an uncertainty quantification model for the infected cases of the pandemic's first wave based on fluid dynamics simulations of the weather effects. The model is physics-based and can rectify a first wave data's inadequacy from a second wave data's adequacy in a pandemic curve. The proposed approach combines environmental seasonality-driven virus transmission rate with pandemic multiwave phenomena to improve statistical predictions' data accuracy. For illustration purposes, we apply the new physics-based model to New York City data.
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Epidemic models do not account for the effects of climate conditions on the transmission dynamics of viruses. This study presents the vital relationship between weather seasonality, airborne virus transmission, and pandemic outbreaks over a whole year. Using the data obtained from high-fidelity multi-phase, fluid dynamics simulations, we calculate the concentration rate of Coronavirus particles in contaminated saliva droplets and use it to derive a new Airborne Infection Rate (AIR) index. Combining the simplest form of an epidemiological model, the susceptible-infected-recovered, and the AIR index, we show through data evidence how weather seasonality induces two outbreaks per year, as it is observed with the COVID-19 pandemic worldwide. We present the results for the number of cases and transmission rates for three cities, New York, Paris, and Rio de Janeiro. The results suggest that two pandemic outbreaks per year are inevitable because they are directly linked to what we call weather seasonality. The pandemic outbreaks are associated with changes in temperature, relative humidity, and wind speed independently of the particular season. We propose that epidemiological models must incorporate climate effects through the AIR index.
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The impact of air ventilation systems on airborne virus transmission (AVT), and aerosols in general, in confined spaces is not yet understood. The recent pandemic has made it crucial to understand the limitations of ventilation systems regarding AVT. We consider an elevator as a prototypical example of a confined space and show how ventilation designs alone, regardless of cooling or heating, contribute to AVT. Air circulation effects are investigated through multiphase computational fluid dynamics, and the performance of an air purifier in an elevator for reducing AVT is assessed. We have investigated three different flow scenarios regarding the position and operation of inlets and outlets in the elevator and a fourth scenario that includes the operation of the air purifier. The position of the inlets and outlets significantly influences the flow circulation and droplet dispersion. An air purifier does not eliminate airborne transmission. The droplet dispersion is reduced when a pair of an inlet and an outlet is implemented. The overall practical conclusion is that the placement and design of the air purifier and ventilation systems significantly affect the droplet dispersion and AVT. Thus, engineering designs of such systems must take into account the flow dynamics in the confined space the systems will be installed.
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Air purifiers are limited to small polluting airborne particles and poor air circulation (fan) for bringing airborne particles inside the device. Thus, the optimal utility of domestic air purifiers (DAPs) for eliminating airborne viruses is still ambiguous. This paper addresses the above limitations using computational fluid dynamics modeling and simulations to investigate the optimal local design of a DAP in an indoor space. We also investigate the integrated fan system and the local transport of airborne viruses. Three different scenarios of using standard DAP equipment ( 144 m 3 / h ) are explored in an indoor space comprising a furnished living room 6 × 6 × 2.5 m 3 . We show that the local positioning of a purifier indoors and the fan system embedded inside it can significantly alter the indoor airborne virus transmission risk. Finally, we propose a new indoor air circulation system that better ensures indoor airborne viruses' local orientation more efficiently than a fan embedded in a standard DAP.
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Our understanding of the mechanisms of airborne transmission of viruses is incomplete. This paper employs computational multiphase fluid dynamics and heat transfer to investigate transport, dispersion, and evaporation of saliva particles arising from a human cough. An ejection process of saliva droplets in air was applied to mimic the real event of a human cough. We employ an advanced three-dimensional model based on fully coupled Eulerian-Lagrangian techniques that take into account the relative humidity, turbulent dispersion forces, droplet phase-change, evaporation, and breakup in addition to the droplet-droplet and droplet-air interactions. We computationally investigate the effect of wind speed on social distancing. For a mild human cough in air at 20 °C and 50% relative humidity, we found that human saliva-disease-carrier droplets may travel up to unexpected considerable distances depending on the wind speed. When the wind speed was approximately zero, the saliva droplets did not travel 2 m, which is within the social distancing recommendations. However, at wind speeds varying from 4 km/h to 15 km/h, we found that the saliva droplets can travel up to 6 m with a decrease in the concentration and liquid droplet size in the wind direction. Our findings imply that considering the environmental conditions, the 2 m social distance may not be sufficient. Further research is required to quantify the influence of parameters such as the environment's relative humidity and temperature among others.
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Face mask filters-textile, surgical, or respiratory-are widely used in an effort to limit the spread of airborne viral infections. Our understanding of the droplet dynamics around a face mask filter, including the droplet containment and leakage from and passing through the cover, is incomplete. We present a fluid dynamics study of the transmission of respiratory droplets through and around a face mask filter. By employing multiphase computational fluid dynamics in a fully coupled Eulerian-Lagrangian framework, we investigate the droplet dynamics induced by a mild coughing incident and examine the fluid dynamics phenomena affecting the mask efficiency. The model takes into account turbulent dispersion forces, droplet phase-change, evaporation, and breakup in addition to the droplet-droplet and droplet-air interactions. The model mimics real events by using data, which closely resemble cough experiments. The study shows that the criteria employed for assessing the face mask performance must be modified to take into account the penetration dynamics of airborne droplet transmission, the fluid dynamics leakage around the filter, and reduction of efficiency during cough cycles. A new criterion for calculating more accurately the mask efficiency by taking into account the penetration dynamics is proposed. We show that the use of masks will reduce the airborne droplet transmission and will also protect the wearer from the droplets expelled from other subjects. However, many droplets still spread around and away from the cover, cumulatively, during cough cycles. Therefore, the use of a mask does not provide complete protection, and social distancing remains important during a pandemic. The implications of the reduced mask efficiency and respiratory droplet transmission away from the mask are even more critical for healthcare workers. The results of this study provide evidence of droplet transmission prevention by face masks, which can guide their use and further improvement.
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The contribution of this paper toward understanding of airborne coronavirus survival is twofold: We develop new theoretical correlations for the unsteady evaporation of coronavirus (CoV) contaminated saliva droplets. Furthermore, we implement the new correlations in a three-dimensional multiphase Eulerian-Lagrangian computational fluid dynamics solver to study the effects of weather conditions on airborne virus transmission. The new theory introduces a thermal history kernel and provides transient Nusselt (Nu) and Sherwood (Sh) numbers as a function of the Reynolds (Re), Prandtl (Pr), and Schmidt numbers (Sc). For the first time, these new correlations take into account the mixture properties due to the concentration of CoV particles in a saliva droplet. We show that the steady-state relationships induce significant errors and must not be applied in unsteady saliva droplet evaporation. The classical theory introduces substantial deviations in Nu and Sh values when increasing the Reynolds number defined at the droplet scale. The effects of relative humidity, temperature, and wind speed on the transport and viability of CoV in a cloud of airborne saliva droplets are also examined. The results reveal that a significant reduction of virus viability occurs when both high temperature and low relative humidity occur. The droplet cloud's traveled distance and concentration remain significant at any temperature if the relative humidity is high, which is in contradiction with what was previously believed by many epidemiologists. The above could explain the increase in CoV cases in many crowded cities around the middle of July (e.g., Delhi), where both high temperature and high relative humidity values were recorded one month earlier (during June). Moreover, it creates a crucial alert for the possibility of a second wave of the pandemic in the coming autumn and winter seasons when low temperatures and high wind speeds will increase airborne virus survival and transmission.
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Multicomponent optical fibers with incorporated metals are promising photonic platforms for engineering of tailored plasmonic structures by laser micromachining or thermal processing. It has been observed that during thermal processing microfluidic phenomena lead to the formation of embedded micro- and nanostructures and spheres, thus triggering the technological motivation for their theoretical investigation, especially in the practical case of noble metal/glass composites that have not yet been investigated. Implemented microwires of gold core and glass cladding, recently studied experimentally, are considered as a reference validation platform. The Plateau-Rayleigh instability in such hybrid fibers is theoretically investigated by inducing surface tension perturbations and by comparing them to the Tomotika instability theory. The continuous-core breakup time was calculated via Finite Element Method (FEM) simulations for different temperatures and was found to be considerably higher to Tomotika's model, while the final sphere diameter is a linear function of the initial core radius. Different sinusoidal perturbation parameters were considered, showing significant impact in the characteristics of formed spherical features. The theoretical results were in close agreement with previous experimental observations expected to assist in the understanding of the processes involved, providing insight into the engineering of fibers, both in the initial drawing process and post processing.
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Turbulence mixing models of different degree of complexity are investigated for Rayleigh-Taylor mixing flows with reference to high-resolution implicit large eddy simulations. The models considered, in order of increasing complexity, comprise the (i) two-equation K-L, (ii) three-equation K-L-a, (iii) four-equation K-L-a-b, and (iv) Besnard-Harlow-Rauenzahn (BHR-2). The above models are implemented in the same numerical framework to minimize the computational uncertainty. The impact of the various approximations represented by the different models is investigated for canonical one-dimensional (1D) Rayleigh-Taylor mixing and for the more complex (2D on average) case of the tilted-rig experiment, aiming to understand the balance between accuracy and complexity. The results provide guidance on the relative merits of various turbulence models over a variety of conditions.
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The aim of this research is to identify possible mechanisms that govern heat transport at a solid-liquid interface using molecular dynamics. The study reveals that, unlike its bulk analogue, a liquid in a nanochannel sustains long-lived collective vibrations, phonons, which propagate over longer timescales and distances. The larger phonon mean free path in nanochannels is attributed to the greater structural order of the liquid atoms and to the larger liquid relaxation time-the time in which the liquid structure remains unchanged and solid-like. For channels of height less than 10 σ , long-range phonons are the dominant means of heat transfer in the directions parallel to the channel walls. The present findings are in agreement with experiments, which have observed significantly increased liquid relaxation times for the same range of channel heights. Finally, it is argued that confinement introduces additional transverse modes of vibration that also contribute to the thermal conductivity enhancement.
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This paper investigates the effect of surface roughness on fluid viscosity using molecular dynamics simulations. The three-dimensional model consists of liquid argon flowing between two solid walls whose surface roughness was modeled using fractal theory. In tandem with previously published experimental work, our results show that, while the viscosity in smooth channels remains constant across the channel width, in the presence of surface roughness it increases close to the walls. The increase of the boundary viscosity is further accentuated by an increase in the depth of surface roughness. We attribute this behavior to the increased momentum transfer at the boundary, a result of the irregular distribution of fluid particles near rough surfaces. Furthermore, although the viscosity in smooth channels has previously been shown to be independent of the strength of the solid-liquid interaction, here we show that in the presence of surface roughness, the boundary viscosity increases with the solid's wettability. The paper concludes with an analytical description of the viscosity as a function of the distance from the channel walls, the walls' surface roughness, and the solid's wetting properties. The relation can potentially be used to adjust the fluid dynamics equations for a more accurate description of microfluidic systems.
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Laminar-to-turbulent transition in pulsatile flow through a stenosis is studied by means of three-dimensional numerical simulations. The flow transition is associated with the occurrence of a flow instability initiating in the stenosis region. The instability is manifested by a three-dimensional symmetry-breaking and leads to asymmetric separation and intense swirling motion downstream of the stenosis. The above have profound effects on the wall shear stress (WSS). The simulations reveal that the asymmetric separation is extended several radii downstream of the stenosis with substantial WSS fluctuations, in both space and time, occurring in the poststenotic region.