Detalhe da pesquisa
1.
Privacy preserving validation for multiomic prediction models.
Brief Bioinform
; 23(3)2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35388408
2.
Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets.
BMC Cancer
; 22(1): 13, 2022 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34979999
3.
Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort.
BMC Cancer
; 22(1): 587, 2022 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35643464
4.
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.
Nucleic Acids Res
; 44(11): e108, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060149
5.
BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data.
Nucleic Acids Res
; 44(4): e38, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578606
6.
Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs.
BMC Genomics
; 17: 65, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26781748
7.
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nat Commun
; 15(1): 4871, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38871738
8.
Contrived Materials and a Data Set for the Evaluation of Liquid Biopsy Tests: A Blood Profiling Atlas in Cancer (BLOODPAC) Community Study.
J Mol Diagn
; 25(3): 143-155, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36828596
9.
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.
Nat Commun
; 13(1): 1667, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35351890
10.
The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells.
NPJ Precis Oncol
; 6(1): 95, 2022 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36575215
11.
DeePaN: deep patient graph convolutional network integrating clinico-genomic evidence to stratify lung cancers for immunotherapy.
NPJ Digit Med
; 4(1): 14, 2021 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33531613
12.
BloodPAC Data Commons for Liquid Biopsy Data.
JCO Clin Cancer Inform
; 5: 479-486, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33929890
13.
A pan-cancer organoid platform for precision medicine.
Cell Rep
; 36(4): 109429, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320344
14.
Identification of Intrinsic Drug Resistance and Its Biomarkers in High-Throughput Pharmacogenomic and CRISPR Screens.
Patterns (N Y)
; 1(5): 100065, 2020 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205120
15.
A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates.
Elife
; 92020 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33274713
16.
Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response.
Clin Cancer Res
; 26(9): 2176-2187, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953314
17.
Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
Nat Commun
; 10(1): 5167, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31727888
18.
MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.
Nat Commun
; 10(1): 2030, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048689
19.
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Nat Commun
; 10(1): 2674, 2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209238
20.
Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer.
Cancer Res
; 78(23): 6691-6702, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297535