Detalhe da pesquisa
1.
Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc Natl Acad Sci U S A
; 119(44): e2210114119, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279441
2.
Trifunctional Saxitoxin Conjugates for Covalent Labeling of Voltage-Gated Sodium Channels.
Chembiochem
; 24(22): e202300493, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37746898
3.
Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel.
Proc Natl Acad Sci U S A
; 117(51): 32711-32721, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277431
4.
Chemical and Biological Tools for the Study of Voltage-Gated Sodium Channels in Electrogenesis and Nociception.
Chembiochem
; 23(13): e202100625, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315190
5.
Silylpyrrole Oxidation En Route to Saxitoxin Congeners Including 11-Saxitoxinethanoic Acid.
J Org Chem
; 86(24): 17790-17803, 2021 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34874731
6.
A selective class of inhibitors for the CLC-Ka chloride ion channel.
Proc Natl Acad Sci U S A
; 115(21): E4900-E4909, 2018 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669921
7.
Mechanistic Study of Ruthenium-Catalyzed C-H Hydroxylation Reveals an Unexpected Pathway for Catalyst Arrest.
J Am Chem Soc
; 141(2): 972-980, 2019 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30601662
8.
Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7.
Proc Natl Acad Sci U S A
; 113(21): 5856-61, 2016 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27162340
9.
Divergent Synthesis of Natural Derivatives of (+)-Saxitoxin Including 11-Saxitoxinethanoic Acid.
Angew Chem Int Ed Engl
; 58(6): 1689-1693, 2019 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30488599
10.
C-H Hydroxylation in Paralytic Shellfish Toxin Biosynthesis.
J Am Chem Soc
; 140(37): 11863-11869, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30192526
11.
Synthetic Studies Toward Pactamycin Highlighting Oxidative C-H and Alkene Amination Technologies.
J Org Chem
; 83(13): 7121-7134, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29708344
12.
Cyanthiwigin Natural Product Core as a Complex Molecular Scaffold for Comparative Late-Stage C-H Functionalization Studies.
J Org Chem
; 83(6): 3023-3033, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29313681
13.
Intermolecular C(sp3 )-H Amination of Complex Molecules.
Angew Chem Int Ed Engl
; 57(18): 4956-4959, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29484792
14.
Ruthenium-Catalyzed C-H Hydroxylation in Aqueous Acid Enables Selective Functionalization of Amine Derivatives.
J Am Chem Soc
; 139(28): 9503-9506, 2017 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28660763
15.
Correction to "Ruthenium-Catalyzed C-H Hydroxylation in Aqueous Acid Enables Selective Functionalization of Amine Derivatives".
J Am Chem Soc
; 143(7): 3016, 2021 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33570914
16.
Synthesis of the Paralytic Shellfish Poisons (+)-Gonyautoxin 2, (+)-Gonyautoxin 3, and (+)-11,11-Dihydroxysaxitoxin.
J Am Chem Soc
; 138(18): 5994-6001, 2016 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27138488
17.
Rh2(II,III) Catalysts with Chelating Carboxylate and Carboxamidate Supports: Electronic Structure and Nitrene Transfer Reactivity.
J Am Chem Soc
; 138(7): 2327-41, 2016 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26820386
18.
Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) [corrected].
Proc Natl Acad Sci U S A
; 109(44): 18102-7, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23077250
19.
Vicinal diamination of alkenes under Rh-catalysis.
J Am Chem Soc
; 136(39): 13506-9, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25233140
20.
Analyzing site selectivity in Rh2(esp)2-catalyzed intermolecular C-H amination reactions.
J Am Chem Soc
; 136(15): 5783-9, 2014 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24673332