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Gynecol Obstet Fertil Senol ; 51(5): 275-283, 2023 05.
Artigo em Francês | MEDLINE | ID: mdl-36924927

RESUMO

Women with a high family risk of breast cancer are those with an identified genetic predisposition or those who have a suggestive family history without an identified germinal mutation, particularly for BRCA1 and BRCA2. Among these women with a very high risk of breast cancer, the fear of a potentially increased risk of breast cancer linked to some hormonal contraceptives and to the use of hormone replacement therapy, in connection with the general population data collected in literature, has led to certain reluctance to prescribe them to these women. Moreover, confusion often sets due to poor knowledge of the literature. Furthermore, the monitoring procedures consist of breast screening and strategies of risk reduction, based on recent recommendations. In order to improve the gynaecological monitoring throughout their lives, we offer here a review based on an analysis of recent literature and of the recommendations concerning personalized screening, contraception and hormone replacement therapy among women with a very high risk of breast cancer free from this illness.


Assuntos
Neoplasias da Mama , Anticoncepcionais , Humanos , Feminino , Detecção Precoce de Câncer , Neoplasias da Mama/genética , Neoplasias da Mama/epidemiologia , Anticoncepção , Terapia de Reposição Hormonal/efeitos adversos , Fatores de Risco
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