Detalhe da pesquisa
1.
Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.
J Neuroinflammation
; 21(1): 108, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38664840
2.
The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats.
Neurobiol Dis
; 148: 105175, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33188920
3.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Neurobiol Dis
; 130: 104525, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276792
4.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
5.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
6.
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.
NPJ Parkinsons Dis
; 10(1): 7, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172128
7.
Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model.
Res Sq
; 2023 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205534
8.
Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease.
bioRxiv
; 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577533
9.
Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.
NPJ Parkinsons Dis
; 8(1): 61, 2022 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35610264
10.
Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein.
Parkinsonism Relat Disord
; 89: 41-47, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34218047
11.
Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo.
J Vis Exp
; (148)2019 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31205308
12.
Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease.
Front Neurosci
; 12: 621, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30233303
13.
Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson's Disease in Rodents.
J Parkinsons Dis
; 8(2): 303-322, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29400668
14.
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.
Sci Rep
; 7(1): 16356, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180681
15.
Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease.
Methods Mol Biol
; 1382: 367-82, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611600