Detalhe da pesquisa
1.
The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aß production.
Cell Mol Life Sci
; 80(4): 97, 2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36930302
2.
The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.
Mol Med
; 22: 905-917, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-28079229
3.
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.
J Cell Sci
; 126(Pt 9): 2124-33, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23447676
4.
Nuclear factor-κB regulates ßAPP and ß- and γ-secretases differently at physiological and supraphysiological Aß concentrations.
J Biol Chem
; 287(29): 24573-84, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22654105
5.
Potentially Pathogenic SORL1 Mutations Observed in Autosomal-Dominant Cases of Alzheimer's Disease Do Not Modulate APP Physiopathological Processing.
Cells
; 12(24)2023 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38132122
6.
The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.
J Biol Chem
; 286(33): 29192-29206, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21586567
7.
Nuclear factor-κB regulates ßAPP and ß- and γ-secretases differently at physiological and supraphysiological Aß concentrations.
J Biol Chem
; 290(50): 29758, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26657754
8.
Therapeutic potential of parkin as a tumor suppressor via transcriptional control of cyclins in glioblastoma cell and animal models.
Theranostics
; 11(20): 10047-10063, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815803
9.
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
Autophagy
; 17(12): 4363-4385, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030589
10.
The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson's Disease Physiopathology.
Cells
; 9(11)2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33212954
11.
The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer's Disease Models.
Cells
; 9(5)2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32408680
12.
Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer's Disease.
Cells
; 8(12)2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31795302
13.
Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis.
Cancer Res
; 66(3): 1313-9, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16452184
14.
The Transcription Factor Function of Parkin: Breaking the Dogma.
Front Neurosci
; 12: 965, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30697141
15.
Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.
Cell Death Differ
; 25(5): 873-884, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352272
16.
ß-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.
Biol Psychiatry
; 83(5): 416-427, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28587718
17.
Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.
Biochem J
; 393(Pt 2): 471-80, 2006 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16176182
18.
Direct α-synuclein promoter transactivation by the tumor suppressor p53.
Mol Neurodegener
; 11: 13, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833254
19.
The transcription factor X-box binding protein-1 in neurodegenerative diseases.
Mol Neurodegener
; 9: 35, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25216759
20.
Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.
J Mol Cell Biol
; 5(2): 132-42, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359614