Detalhe da pesquisa
1.
A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy.
Bioconjug Chem
; 33(6): 1210-1221, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658441
2.
Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target.
Cancers (Basel)
; 12(1)2020 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947537
3.
Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.
J Med Chem
; 63(15): 8025-8042, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338514
4.
Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.
J Med Chem
; 62(2): 928-940, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30563338
5.
Structural basis for a high affinity inhibitor bound to protein kinase MK2.
J Mol Biol
; 369(3): 735-45, 2007 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17449059
6.
Identifying protein construct variants with increased crystallization propensity--a case study.
Protein Sci
; 15(12): 2718-28, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17132859
7.
Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.
Acta Crystallogr D Biol Crystallogr
; 64(Pt 4): 339-53, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18391401