Detalhe da pesquisa
1.
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34479993
2.
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes.
Nature
; 483(7391): 589-93, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367537
3.
Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Genes Chromosomes Cancer
; 51(1): 10-9, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22034077
4.
MEK inhibition causes BIM stabilization and increased sensitivity to BCL-2 family member inhibitors in RAS-MAPK-mutated neuroblastoma.
Front Oncol
; 13: 1130034, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36895472
5.
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.
Proc Natl Acad Sci U S A
; 106(31): 12968-73, 2009 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525400
6.
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma.
J Clin Invest
; 130(11): 5875-5892, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33016930
7.
RAS-MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma.
Cancer Res
; 78(21): 6297-6307, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30115695
8.
Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity.
Eur J Cancer
; 75: 63-72, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28214660
9.
Neuroblastoma is composed of two super-enhancer-associated differentiation states.
Nat Genet
; 49(8): 1261-1266, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28650485
10.
Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma.
Clin Cancer Res
; 21(22): 5100-9, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26202950
11.
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
Nat Genet
; 47(8): 864-71, 2015 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26121087
12.
Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours.
Eur J Cancer
; 50(3): 628-37, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24321263
13.
Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth.
Eur J Cancer
; 48(16): 3093-103, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366560
14.
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Nat Genet
; 44(11): 1199-206, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042116
15.
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe.
Endocr Relat Cancer
; 18(6): 657-68, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21859926
16.
Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.
Cancer Res
; 68(8): 2599-609, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18413728
17.
Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
Blood
; 101(4): 1270-6, 2003 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12406912