Detalhe da pesquisa
1.
Novel spiroindoline quinazolinedione derivatives as anticancer agents and potential FLT3 kinase inhibitors.
Bioorg Med Chem
; 90: 117367, 2023 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348260
2.
5-Oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine derivatives as promising antiproliferative agents with potential apoptosis-inducing capacity.
Mol Divers
; 26(3): 1481-1500, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671894
3.
Synthesis and evaluation of novel arylisoxazoles linked to tacrine moiety: in vitro and in vivo biological activities against Alzheimer's disease.
Mol Divers
; 26(1): 409-428, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34273065
4.
Imino-2H-Chromene Based Derivatives as Potential Anti-Alzheimer's Agents: Design, Synthesis, Biological Evaluation and in Silico Study.
Chem Biodivers
; 19(1): e202100599, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34786830
5.
Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies.
Bioorg Chem
; 109: 104684, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33607363
6.
Anti-melanogenesis and anti-tyrosinase properties of aryl-substituted acetamides of phenoxy methyl triazole conjugated with thiosemicarbazide: Design, synthesis and biological evaluations.
Bioorg Chem
; 114: 104979, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140181
7.
Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents.
Arch Pharm (Weinheim)
; 354(3): e2000258, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33226157
8.
Design, synthesis, in vitro and in silico studies of novel Schiff base derivatives of 2-hydroxy-4-methoxybenzamide as tyrosinase inhibitors.
Drug Dev Res
; 82(4): 533-542, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340117
9.
One-pot synthesis of thioxo-tetrahydropyrimidine derivatives as potent ß-glucuronidase inhibitor, biological evaluation, molecular docking and molecular dynamics studies.
Bioorg Med Chem
; 28(7): 115359, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32098709
10.
Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands.
Bioorg Chem
; 97: 103649, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101780
11.
N-Cyclohexylimidazo[1,2-a]pyridine derivatives as multi-target-directed ligands for treatment of Alzheimer's disease.
Bioorg Chem
; 103: 104146, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32777579
12.
5,6-Diphenyl triazine-thio methyl triazole hybrid as a new Alzheimer's disease modifying agents.
Mol Divers
; 24(3): 641-654, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31327094
13.
Design, synthesis, in vivo and in vitro studies of 1,2,3,4-tetrahydro-9H-carbazole derivatives, highly selective and potent butyrylcholinesterase inhibitors.
Mol Divers
; 24(1): 211-223, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30927138
14.
A Series of Benzylidenes Linked to Hydrazine-1-carbothioamide as Tyrosinase Inhibitors: Synthesis, Biological Evaluation and Structure-Activity Relationship.
Chem Biodivers
; 17(8): e2000285, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32478439
15.
Design and Synthesis of Novel Arylisoxazole-Chromenone Carboxamides: Investigation of Biological Activities Associated with Alzheimer's Disease.
Chem Biodivers
; 17(5): e1900746, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32154628
16.
1,2,3-Triazole-linked 5-benzylidene (thio)barbiturates as novel tyrosinase inhibitors and free-radical scavengers.
Arch Pharm (Weinheim)
; 353(10): e2000058, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32638438
17.
Thieno[2,3-b]pyridine amines: Synthesis and evaluation of tacrine analogs against biological activities related to Alzheimer's disease.
Arch Pharm (Weinheim)
; 353(10): e2000101, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32657467
18.
5-Oxo-hexahydroquinoline Derivatives and Their Tetrahydroquinoline Counterparts as Multidrug Resistance Reversal Agents.
Molecules
; 25(8)2020 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32316291
19.
Prediction of cytotoxic activity of a series of 1H-pyrrolo[2,3-b]pyridine derivatives as possible inhibitors of c-Met using molecular fingerprints.
J Recept Signal Transduct Res
; 39(4): 295-303, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31658862
20.
5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells.
Toxicol Appl Pharmacol
; 362: 136-149, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30391378