Detalhe da pesquisa
1.
Pharmacokinetic/pharmacodynamic investigation of raltegravir with or without lamivudine in the context of HIV-1 pre-exposure prophylaxis (PrEP).
J Antimicrob Chemother
; 76(8): 2129-2136, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33993302
2.
AUTOSTERE: Systematic Search for Scaffold Replacement Opportunities within Structural Databases.
J Chem Inf Model
; 61(4): 1778-1788, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830752
3.
A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670438
4.
Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28461315
5.
Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis.
Antimicrob Agents Chemother
; 60(1): 617-20, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26482301
6.
Effect of intermittent rifampicin on the pharmacokinetics and safety of raltegravir.
J Antimicrob Chemother
; 70(2): 550-4, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25261424
7.
CYP3A4*22 (c.522-191 C>T; rs35599367) is associated with lopinavir pharmacokinetics in HIV-positive adults.
Pharmacogenet Genomics
; 24(9): 459-63, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24950369
8.
Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients.
J Antimicrob Chemother
; 69(2): 491-9, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24080498
9.
Plasma and intracellular (peripheral blood mononuclear cells) pharmacokinetics of once-daily raltegravir (800 milligrams) in HIV-infected patients.
Antimicrob Agents Chemother
; 55(1): 72-5, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937791
10.
The SLCO1B1 rs4149032 polymorphism is highly prevalent in South Africans and is associated with reduced rifampin concentrations: dosing implications.
Antimicrob Agents Chemother
; 55(9): 4122-7, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21709081
11.
Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals.
J Antimicrob Chemother
; 66(6): 1332-9, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21441248
12.
Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens.
J Antimicrob Chemother
; 66(9): 2092-8, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21715435
13.
HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.
Pharmacogenet Genomics
; 20(2): 112-20, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20051929
14.
Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study.
Clin Infect Dis
; 48(11): e108-16, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19400747
15.
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients.
J Antimicrob Chemother
; 61(4): 914-8, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18281305
16.
Polymorphisms of tenofovir disoproxil fumarate transporters and risk of kidney tubular dysfunction in HIV-positive patients: genetics of tenofovir transporters.
Int J STD AIDS
; : 956462418786562, 2018 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30071797
17.
Validation and clinical application of a novel LC-MS method for quantification of dolutegravir in breast milk.
Bioanalysis
; 10(23): 1933-1945, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30450920
18.
Cytotoxic chemotherapy and the evolution of cellular and viral resistance to antiretroviral therapy in HIV- infected individuals with lymphoma.
HIV Clin Trials
; 17(5): 197-203, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27454119
19.
The development and application of a novel LC-MS/MS method for the measurement of Dolutegravir, Elvitegravir and Cobicistat in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1027: 174-80, 2016 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27290668
20.
Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.
J Acquir Immune Defic Syndr
; 73(3): 252-257, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27727157